Results 91 to 100 of about 1,342,018 (289)

Tetrodotoxin-Producing Bacteria: Detection, Distribution and Migration of the Toxin in Aquatic Systems

Toxins, 2017
This review is devoted to the marine bacterial producers of tetrodotoxin (TTX), a potent non-protein neuroparalytic toxin. In addition to the issues of the ecology and distribution of TTX-producing bacteria, this review examines issues relating to toxin ...
Timur Yu. Magarlamov, Daria I. Melnikova, Alexey V. Chernyshev   +2 more
doaj   +1 more source

Patterns of Post-Glacial Genetic Differentiation in Marginal Populations of a Marine Microalga [PDF]

, 2012
This study investigates the genetic structure of an eukaryotic microorganism, the toxic dinoflagellate Alexandrium ostenfeldii, from the Baltic Sea, a geologically young and ecologically marginal brackish water estuary which is predicted to support ...
Kremp, A., John, Uwe, Päivi Hakanen (107373), Jaanika Blomster (107376), Tilman J Alpermann, Figueroa Rosa Isabel, Tilman J. Alpermann (107367), Uwe John (107371), Tilman J. Alpermann, Satoshi Nagai, Anke Kremp, Kremp Anke, Nagai, S. (Shatoshi), Hakanen Päivi, Figueroa, Rosa, Jaanika Blomster, Pia Tahvanainen, Blomster, J, Tahvanainen, P, Tahvanainen, P. (Pia), Hakanen, P., Nagai Satoshi, Alpermann Tilman J., Figueroa, Rosa Isabel, Hakanen, P, Alpermann, Tilman J., Kremp, Anke, Pia Tahvanainen, Figuera, R.I., Nagai, Satoshi, Figueroa, R.I. (Rosa Isabel), Uwe John, Alpermann, Tilman Jens, Blomster, Jaanika, Alpermann , Tilman J., Alpermann, T.J., Päivi Hakanen, Nagai, Shatoshi, Pia Tahvanainen (107364), Uwe, J., Blomster, J., Nagai, S., Rosa Isabel Figueroa (107369), Tahvanainen Pia, Tahvanainen, Pia, John Uwe, Anke Kremp (107378), Rosa Isabel Figueroa, Blomster Jaanika, Hakanen, Päivi, Satoshi Nagai (72562)   +50 more
core   +2 more sources

The Anemonia viridis Venom: Coupling Biochemical Purification and RNA-Seq for Translational Research

Marine Drugs, 2018
Blue biotechnologies implement marine bio-resources for addressing practical concerns. The isolation of biologically active molecules from marine animals is one of the main ways this field develops.
Aldo Nicosia, Alexander Mikov, Matteo Cammarata, Paolo Colombo, Yaroslav Andreev, Sergey Kozlov, Angela Cuttitta   +6 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Marine Biotechnology Task Force Report [PDF]

, 2017
Marine biotechnology is a rapidly growing area that is recognised, by policy makers and the enterprise sector, as offering significant potential to develop market opportunities for new products and processes by enabling greater utilisation of marine ...
Marine Biotechnology Task
core   +2 more sources

Exploring potentially synthetic genes related to diarrhetic shellfish toxins production in Prorocentrum sp. via comparative transcriptomics

Ecotoxicology and Environmental Safety
Harmful algal blooms (HABs), exacerbated by climate change and environmental disturbances, pose global challenges due to marine toxin contamination, particularly diarrhetic shellfish toxins (DSTs).
Danlin Zheng, Jingyi Cen, Peiliang Chen, Ligong Zou, Jian Zou, Qun Li, Songhui Lu   +6 more
doaj   +1 more source

Novel and Efficient Synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido Oximes. Part 3.

Molecules, 2007
A novel and efficient method has been developed for the synthesis of N,N-dialkylamino-O-alkyl-2-(1-methyl-2-oxopropylidene)phosphorohydrazido oximes 5.
Mahabir P. Kaushik, Arvind K. Gupta, Rajesh Kumar   +2 more
doaj   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

Angewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley, Michael Rust, Moritz Wagner, Ida R. Hipfinger, Paul J. N. Böhm, Cora L. Dieterich, Christopher M. Field, Michael J. Page, Jeremy G. Owen, Robert A. Keyzers, Shinichi Sunagawa, Jörn Piel   +11 more
wiley   +2 more sources

Engineering Morphological Anisotropy to Control the In Vivo Transport Dynamics, Clearance, and Biodistribution of Silica Nanocarriers

Advanced Science, EarlyView.
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li, Yingjie Yu, Tianchang He, Xiaoyan Fang, Wenhua Yang, Luying Zhou, Hao Fan, Guimei Lin, Daniel Crespy, Katharina Landfester, Junfeng Zhang, Shuai Jiang   +11 more
wiley   +1 more source