Computational Studies of Marine Toxins Targeting Ion Channels [PDF]
Marine Drugs, 2013 Toxins from marine animals offer novel drug leads for treatment of diseases involving ion channels. Computational methods could be very helpful in this endeavour in several ways, e.g., (i) constructing accurate models of the channel-toxin complexes using
Serdar Kuyucak +2 more
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Exploring marine toxins: comparative analysis of chemical reactivity properties and potential for drug discovery [PDF]
Frontiers in Chemistry, 2023 Marine toxins, produced by various marine microorganisms, pose significant risks to both marine ecosystems and human health. Understanding their diverse structures and properties is crucial for effective mitigation and exploration of their potential as ...
Norma Flores-Holguín +4 more
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Voltage-Gated Sodium Channels: A Prominent Target of Marine Toxins [PDF]
Marine Drugs, 2021 Voltage-gated sodium channels (VGSCs) are considered to be one of the most important ion channels given their remarkable physiological role. VGSCs constitute a family of large transmembrane proteins that allow transmission, generation, and propagation of
Rawan Mackieh +6 more
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Emergent marine toxins risk assessment using molecular and chemical approaches [PDF]
EFSA Journal, 2022 Cyanobacteria harmful blooms represent a deviation to the normal equilibrium in planktonic communities involving a rapid and uncontrolled growth. Owing to the capacity to produce toxins as secondary metabolites, cyanobacteria may cause huge economic ...
Y García‐Cazorla, V Vasconcelos
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Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds [PDF]
Marine Drugs, 2020 Toxins from marine animals provide molecular tools for the study of many ion channels, including mammalian voltage-gated potassium channels of the Kv1 family.
Rocio K. Finol-Urdaneta +5 more
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Analyzing European Union Rapid Alert System (RASFF) Notifications of Emerging Marine and Freshwater Toxins from the Last Decade: Appearance Trends and Links with Occurrence Data and Risk Assessment Advancements [PDF]
Biology and Life Sciences Forum, 2023 The EU Rapid Alert System for Food and Feed (RASFF) is a tool for the rapid exchange of information on food and feed safety issues between EU member states and the European Commission, destined to notify food safety authorities about products posing a ...
Panagiota Katikou
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Extended Targeted and Non-Targeted Strategies for the Analysis of Marine Toxins in Mussels and Oysters by (LC-HRMS) [PDF]
Toxins, 2018 When considering the geographical expansion of marine toxins, the emergence of new toxins and the associated risk for human health, there is urgent need for versatile and efficient analytical methods that are able to detect a range, as wide as possible ...
Inès Dom +5 more
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Exploration of Toxins from a Marine Annelid: An Analysis of Phyllotoxins and Accompanying Bioactives [PDF]
AnimalsProteinaceous toxins are peptides or proteins that hold great biotechnological value, evidenced by their ecological role, whether as defense or predation mechanisms.
Ana P. Rodrigo +3 more
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Commemorating the Launch of the Section “Marine Toxins” [PDF]
Marine DrugsMarine toxins are natural compounds produced by a variety of marine organisms, including microalgae, bacteria, and macroalgae [...]
Andrew Turner, Panagiota Katikou
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Marine Toxins as Pharmaceutical Treasure Troves: A Focus on Saxitoxin Derivatives from a Computational Point of View [PDF]
MoleculesThis work highlights the significant potential of marine toxins, particularly saxitoxin (STX) and its derivatives, in the exploration of novel pharmaceuticals.
Norma Flores-Holguín +4 more
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