Results 41 to 50 of about 313,260 (253)

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Marion County Notice of Adopted Amendment (2009-04-29) [PDF]

, 2009
282 pp. Adopted 2009-04-29. Department of Land Conservation and Development Notice of Adopted AmendmentAMENDMENTS TO THE TEXT OF THE MARION COUNTY RURAL ZONING ORDINANCE NO 516 TO UPDATE CODE DUE TO NEW LEGISLATION GENERAL CLEAN UP AND MODIFICATION TO ...
Marion County (Or.)
core   +3 more sources

Substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters

Journal of Lipid Research, 1999
The substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters was determined using brush border membrane vesicles and CHO cell lines permanently expressing the Na+/bile acid cotransporters from rabbit ileum or rabbit liver.
Werner Kramer, Siegfried Stengelin, Karl-Heinz Baringhaus, Alfons Enhsen, Hubert Heuer, Wolfgang Becker, Daniel Corsiero, Frank Girbig, Rüdiger Noll, Claudia Weyland   +9 more
doaj   +1 more source

The borders of phenomenality [PDF]

Filozofija i Društvo, 2016
This text is based on the lecture held by Jean-Luc Marion at the Institute for Philosophy and Social Theory (University of Belgrade), on December 4., 2015. By thematizing the “limits of phenomenality”, Marion analyzes what exceeds the horizon of
Marion Jean-Luc
doaj   +1 more source

Limitations of Foundation Models in Energy Materials Simulations: A Case Study in Polyanion Sodium Cathode Materials

Advanced Intelligent Discovery, EarlyView.
Several simulation techniques are used to explore static and dynamic behavior in polyanion sodium cathode materials. The study reveals that universal machine learning interatomic potentials (MLIPs) struggle with system‐specific chemistry, emphasizing the need for tailored datasets.
Martin Hoffmann Petersen, Chiku Parida, Jonas Busk, Jin Hyun Chang, Arghya Bhowmik, Juan Maria Garcia Lastra   +5 more
wiley   +1 more source

A Laboratory Activity Demonstrating the Antibacterial Effects of Extracts from Two Plant Species, Moringa oleifera and Allium sativum (Garlic)

Journal of Microbiology & Biology Education, 2017
A variety of plants synthesize natural products that either kill or inhibit the growth of various microorganisms. These plant products may serve as useful natural alternatives to synthetic antimicrobial pharmaceuticals and can be especially important in ...
Grace J. Miller, Anna M. G. Cunningham, Yui Iwase, Nicole L. Lautensack, W. Matthew Sattley   +4 more
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

American Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording, Erik W. Ertsgaard, David E. Giblin, Iris H. Dimpsey, Owen B. Bard   +4 more
wiley   +1 more source

Biodiversity and culture of prokaryotes inhabiting haloalkaline and meromictic Soap Lake, Washington, USA

Frontiers in Microbiology
Despite their potential for harboring novel microorganisms exhibiting beneficial metabolisms or that produce useful products for biotechnology and industry, alkaline lakes and soils are among the least studied extreme environments.
Olivia J. M. Vanderlaan, Emily M. Simmons, Kelli M. Damman, Makenna D. Waddell, Savannah F. Ross, Amanda D. Armstrong, Mackenzie L. Walker, S. Josiah Sattley, W. Matthew Sattley   +8 more
doaj   +1 more source