Results 101 to 110 of about 19,662 (283)

Co-phonology vs. Indexed constraint theory: a case study of Perak dialect partial reduplication [PDF]

, 2012
This paper presents co-phonologies and indexed constraint theory developed within Optimality theory (Prince and Smolensky, 1993) to account for partial reduplication in Perak dialect of Malay.
Syed Jaafar, Sharifah Raihan
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Marked or unmarked, that is not the question. The question is: where’s the theme? Marked or unmarked, that is not the question. The question is: where’s the theme?

Ilha do Desterro, 2008
The definition of theme is not entirely uncontroversial within systemic linguistics. Furthermore, the application of the notion of theme to languages other than English is even more problematic.
Carlos A. M. Gouveia, Leila Barbara
doaj  

The Syncategorematic Nature of Neo-Aramaic and English Antonyms

Linguistic Discovery, 2018
Antonyms have always been considered the starting point for language learners; therefore, they are familiar cross-linguistically. In this research, we try to provide a semantic description of antonymy in Neo-Aramaic (a member of the Semitic family) as it
Ala Al-Kajela
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Covert contrast as a developmental stage in L2 phonology: evidence from Arabic emphatics

Cogent Arts & Humanities
This study examines covert contrasts—acoustically distinct yet imperceptible phonemic differences—in English-speaking learners of Modern Standard Arabic, focusing on /tˤ/–/t/ and /sˤ/–/s/.
Mohammad Aljutaily, Radhyah Almutairi
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Coseriu et Hjelmslev sur la théorie de la marque. Éléments pour continuer le dialogue

Histoire Épistémologie Langage
One may rightly assume that Eugenio Coseriu’s integral linguistics and Louis Hjelmslev’s glossematics represent two keys to a mutual understanding. On the one hand, Coseriu’s criticism towards certain aspects of glossematics proves useful for better ...
Lorenzo Cigana
doaj   +1 more source

Morphological transparency and markedness matter in heritage speaker gender processing: an EEG study. [PDF]

Front Psychol, 2023
Luque A, Rossi E, Kubota M, Nakamura M, Rosales C, López-Rojas C, Rodina Y, Rothman J, Rothman J.   +8 more
europepmc   +1 more source