Results 51 to 60 of about 4,652,084 (286)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Weak Allele of FASCIATED EAR 2 (FEA2) Increases Maize Kernel Row Number (KRN) and Yield in Elite Maize Hybrids

Agronomy, 2020
Meristems are central to plant growth and development, yet evidence of directly manipulating this control to improve crop yield is scarce. Kernel row number (KRN) is an important agronomic trait that can directly affect maize (Zea mays L.) yield. However,
Khuat Huu Trung, Quan Hong Tran, Ngoc Hong Bui, Thuy Thi Tran, Kong Quy Luu, Nga Thi Thu Tran, Loan Thi Nguyen, Diep Thi Ngoc Nguyen, Bach Duong Vu, Duong Thi Thuy Quan, Diep Thuy Nguyen, Hien Thi Nguyen, Cuong Cao Dang, Bao Manh Tran, Tran Dang Khanh, Son Lang Vi   +15 more
doaj   +1 more source

The ovine HIAT1 gene: mRNA expression, InDel mutations, and growth trait associations

Frontiers in Veterinary Science, 2023
BackgroundThe hippocampal abundant transcript 1 (HIAT1) gene, also known as major facilitator superfamily domain-containing 14A (MFSD14A), encodes for a transmembrane transporter protein and has been previously shown to be associated with milk production
Yunyun Luo, Zhanerke Akhatayeva, Cui Mao, Cui Mao, Fugui Jiang, Zhengang Guo, Hongwei Xu, Xianyong Lan   +7 more
doaj   +1 more source

Application Marker-Assisted Selection (MAS) and Multiplex PCR Reactions in Resistance Breeding of Maize (Zea mays L.)

Agriculture, 2022
Cultivated maize (Zea mays L.) is the oldest and one of the most important crop species in the world. Changing climatic conditions in recent years, warm weather, expansion of acreage and intensification of maize cultivation have resulted in an increase in the threat posed by diseases caused by, among others, Fusarium fungi.
Aleksandra Sobiech, Agnieszka Tomkowiak, Jan Bocianowski, Bartosz Nowak, Dorota Weigt, Danuta Kurasiak-Popowska, Michał Kwiatek, Sylwia Mikołajczyk, Janetta Niemann, Katarzyna Szewczyk   +9 more
openaire   +2 more sources

Average prediction accuracy of four genomic selection methods and marker assisted selection (MAS) for six seed quality traits of the TN DH population.

, 2016
Average prediction accuracy of four genomic selection methods and marker assisted selection (MAS) for six seed quality traits of the TN DH population.
Jinling Meng (118331), Lei Shi (1235181), Xiaohua Wang (255149), Jun Zou (683), Yusheng Zhao (388357), Meng Wang (124646), Jochen Christoph Reif (3360785), Peifa Liu (3294570)   +7 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Challenges for effective marker-assisted selection in plants

, 2009
International audienceThe basic principle of Marker-Assisted Selection (MAS) is to exploit Linkage Disequilibrium (LD) between markers and QTLs. With strong enough LD, MAS should in theory be easier, faster, cheaper, or more efficient than classical ...
Hospital, Frederic, F.
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Introgression of Striga Resistance Genes into a Sudanese Sorghum Cultivar, Tabat, Using Marker Assisted Selection (MAS) [PDF]

Greener Journal of Agricultural Sciences, 2013
Resistant crop cultivars provide the most economical, practical and sustainable method of Striga control. However, the development of resistant sorghum cultivars slowed by the complexity of the environment and the host/parasite interactions, which made field resistance erratic and unreliable.
Yasir, Ahmed Gamar, Abdalla, Hassan Mohamed   +1 more
openaire   +2 more sources