Results 71 to 80 of about 42,796 (299)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Potential for marker-assisted selection for forest tree breeding: lessons from 20 years of MAS in crops

Tree Genetics & Genomes, 2014
For the most part, molecular markers and detection of quantitative trait loci have been developed for forest tree species in view to performing marker-assisted selection (MAS). However, MAS has not been applied to forest trees until now. In parallel, some success stories of MAS in crop breeding have been reported.
Muranty, Helene, Jorge, Véronique, V., Bastien, Catherine, Lepoittevin, Camille, Bouffier, Laurent, Sanchez Rodriguez, Leopoldo   +5 more
openaire   +4 more sources

Statistical analysis of the associations between phenolic monoterpenes and molecular markers, AFLPs and SAMPLs in the spice plant Oregano

Herba Polonica, 2016
Introduction: Molecular markers are the examples of the contribution of genome technology to medicinal plant breeding through marker-assisted selection (MAS) for pharmaceutical quality.
Azizi Ali, Ardalani Hamidreza, Honermeier Bernd   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Effectiveness of applying different methods of molecular genetics in swine selection (A review)

Животновъдни науки, 2023
The rapid development of molecular genetics in the last two decades, primarily related to the technological breakthrough in the field of genome sequencing of higher organisms, has made it possible to apply new models of work.
Katya Eneva, Apostol Apostolov
doaj  

Fine Mapping of Lycopene Content and Flesh Color Related Gene and Development of Molecular Marker–Assisted Selection for Flesh Color in Watermelon (Citrullus lanatus)

Frontiers in Plant Science, 2019
Lycopene content and flesh color are important traits determined by a network of carotenoid metabolic pathways in watermelon. Based on our previous study of genetic inheritance and initial mapping using F2 populations of LSW-177 (red flesh) × cream of ...
Chaonan Wang, Chaonan Wang, Aohan Qiao, Aohan Qiao, Xufeng Fang, Xufeng Fang, Lei Sun, Lei Sun, Peng Gao, Peng Gao, Angela R. Davis, Shi Liu, Shi Liu, Feishi Luan, Feishi Luan   +14 more
doaj   +1 more source

Fine Mapping of the Wheat Leaf Rust Resistance Gene LrLC10 (Lr13) and Validation of Its Co-segregation Markers

Frontiers in Plant Science, 2020
Wheat leaf rust, caused by the fungus Puccinia triticina Eriks. (Pt), is a destructive disease found throughout common wheat production areas worldwide.
Lina Qiu, Huifang Wang, Yinghui Li, Yinghui Li, Weidong Wang, Yujia Liu, Junyi Mu, Miaomiao Geng, Miaomiao Geng, Weilong Guo, Zhaorong Hu, Jun Ma, Qixin Sun, Chaojie Xie   +13 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Introgression of Two Quantitative Trait Loci for Stripe Rust Resistance into Three Chinese Wheat Cultivars

Agronomy, 2020
Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most devastating diseases in wheat. Due to the large-scale and widely-distributed planting pattern of wheat, the directional selection pressure of the pathogen is very ...
Tian Hu, Xiao Zhong, Qiang Yang, Xinli Zhou, Xin Li, Suizhuang Yang, Lu Hou, Qiang Yao, Qingyun Guo, Zhensheng Kang   +9 more
doaj   +1 more source

Marker Assisted Selection (MAS) and It's Application in Vegetable Crop Improvement

International Journal of Plant & Soil Science
Vegetable crop breeding has changed dramatically since the early 1980s due to technological breakthroughs, especially high-throughput sequencing and molecular marker technologies, which have made it possible to sequence many plant genomes, create dense genetic maps, and identify important genes and QTLs linked to traits like yield and disease ...
Varun Shekhar, Vijay Bahadur, Lalita Lal
openaire   +1 more source