Results 161 to 170 of about 3,952,373 (303)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Immunohistochemical Markers of Mitochondrial Electron Transport Chain Instability in Human Brain Regions: A Study of Aging and Alzheimer's Disease. [PDF]

Int J Mol Sci
Baranich TI, Sukhorukov VS, Velts OV, Voronkov DN, Shcherbak EV, Egorova AV, Romanenko AS, Lazarev DS, Raksha AP, Charyeva IG, Yatskovskiy AN, Glinkina VV, Illarioshkin SN.   +12 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Inorganic Photoluminescent Microparticles as Identifiers for the Sorting of Lithium-Ion Battery Cathodes. [PDF]

ChemSusChem
Ziegler S, Strohhöfer C, Gao G, Flegler A, Giffin GA.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Genome-wide association studies for identifying SNPs and candidate genes associated with grain quality traits in rice (Oryza sativa L.). [PDF]

Plant Genome
Darmagaru S, Rahaman AF, Jabeen F, Jukanti AK, Kasarla C, Gowdru Dhananjaya DK, Tamilarasu A, Subba Rao L, Kallakuri S, Venkatanagappa S, Sundaram RM.   +10 more
europepmc   +1 more source

Informing groundwater model hydrostratigraphy with airborne time-domain electromagnetic data and borehole logs [PDF]

, 2016
Marker, Pernille Aabye
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Obituary for Giuliano Rodolfi

Investigaciones Geográficas, 2015
Michael Märker
doaj   +1 more source

Limitations of Common Molecular Markers in Fungal Biodiversity Analysis and the Benefits of Their Synergistic Use. [PDF]

Mol Ecol Resour
Shapkin V, Zelenka T, Větrovský T, Kostovčík M, Eichlerová I, Kohout P, Žifčáková L, Borovička J, Tomšovský M, Adamčík S, Baldrian P, Kolařík M.   +11 more
europepmc   +1 more source