Gastric cancer (GC) is a significant public health burden worldwide, and cisplatin resistance is the leading cause for the failure of chemotherapy in this disease. Previous studies have revealed that HOXA transcript at the distal tip (HOTTIP) is involved
Rui Zhao +18 more
doaj +1 more source
Impact of knee marker misplacement on gait kinematics of children with cerebral palsy using the Conventional Gait Model — a sensitivity study [PDF]
Clinical gait analysis is widely used in clinical routine to assess the function of patients with motor disorders. The proper assessment of the patient’s function relies greatly on the repeatability between the measurements.
Armand, S +4 more
core +5 more sources
Kleomenes I of Sparta: A Proto-Biography [PDF]
Claims that Herodotus reveals himself as a proto-biographer are not yet widely accepted. To advance this claim, I review his recount of Kleomenes of Sparta (c. 540–c.
Oliver R. Baker
doaj +1 more source
On the Use of Marker Strategy Design to Detect Predictive Marker Effect in Cancer Immunotherapy [PDF]
Indiana University-Purdue University Indianapolis (IUPUI)The marker strategy design (MSGD) has been proposed to assess and validate predictive markers for targeted therapies and immunotherapies.
Han, Yan
core +1 more source
Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [PDF]
Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of human pedigrees.
Abecasis, Gonçalo R. +1 more
openaire +2 more sources
The clinical value of serum TPS in gynecological malignancies
This study included 75 cases; 39 with gynecological cancer of different types, stages, and grades (14 ovarian, 11 endometrial, 9 cervical, and 5 vulvovaginal); 23 patients with benign gynecological diseases and 13 normal healthy controls.
T. Salman +3 more
doaj +1 more source
TPS Monitoring in Metastatic Breast Cancer
The management of metastatic breast cancer patients reflects the heterogeneous nature of the disease. While patients may benefit from hormonal treatment, in most cases more toxic chemotherapy is applied in the advanced stages.
A. Van Dalen
doaj +1 more source
S100 Beta as a Marker of Section Hepatic Encephalopathy: A Case-control Study [PDF]
Introduction: Hepatic Encephalopathy (HE) is a term used to describe a reversible syndrome of impaired brain function involving a complex spectrum of non specific neurological and psychiatric manifestations occurring in patients of severe acute or ...
Manish Chandey +3 more
doaj +1 more source
pH-Responsive DNA Motif: From Rational Design to Analytical Applications
pH-responsive DNA motifs have attracted substantial attention attributed to their high designability and versatility of DNA chemistry. Such DNA motifs typically exploit DNA secondary structures that exhibit pH response properties because of the presence ...
Lin Lin Zheng +5 more
doaj +1 more source
On how 'middle' plus 'associative/reciprocal' became 'passive' in the Bantu A70 languages [PDF]
In this paper we show that the Bantu A70 languages did not preserve the passive morpheme inherited from Proto-Bantu (PB), but developed a new suffix. It is a morpheme that is compound in origin, consisting of two verbal derivation suffixes which still ...
Bostoen, Koen, Nzang-Bie, Yolande
core +1 more source

