Results 171 to 180 of about 270,162 (309)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Transfer of Meloidogyne incognita Resistance Using Marker-assisted Selection in Sorghum. [PDF]

J Nematol, 2021
Davis RF, Harris-Shultz KR, Knoll JE, Wang H.   +3 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Predictive breeding and marker-assisted selection for grain quality and freezing tolerance in durum wheat. [PDF]

Front Plant Sci
Habib Y, Angione G, Vitale P, Baneh H, Natoli V, Lotti C, Dolaberidze SD, Bespalova LA, Mudrova AA, Ianovskii AS, Esposito S, De Vita P.   +11 more
europepmc   +1 more source

Quantitative trait loci associated with straighthead-resistance used for marker assisted selection in rice (Oryza sativa L.) RIL populations. [PDF]

PeerJ, 2023
Pan X, Li Y, Li X.
europepmc   +1 more source

Marker-Assisted Selection Backgrounder

, 2004
DNA (deoxyribonucleic acid) is a molecule that is shaped like a double helix and made up of pairs of nucleotides. DNA transmits genetic information. DNA is packaged into chromosomes which are located within the nucleus of all cells. Every cell in the body contains all of the chromosomes that collectively make up the genome of that organism.
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Developing a model to implement marker-assisted selection for root-knot nematode resistance in common bean. [PDF]

G3 (Bethesda)
Floriani TO, Gama HC, Moreno BM, Costa GAL, Giordani W, Chiorato AF, Bibiano L, Parker TA, Camargo LEA, Vieira MLC, Garcia AAF.   +10 more
europepmc   +1 more source

Improving blast resistance of maintainer line DRR 9B by transferring broad spectrum resistance gene Pi2 by marker assisted selection in rice. [PDF]

Physiol Mol Biol Plants, 2023
Singh AK, Ponnuswamy R, Srinivas Prasad M, Sundaram RM, Hari Prasad AS, Senguttuvel P, Kempa Raju KB, Sruthi K.   +7 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source