Results 201 to 210 of about 95,506 (252)
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1978
Publisher Summary This chapter is concerned with virus vaccines and their genetically conditioned markers. For many years, virus vaccines have been in fact the only effective means for reducing the morbidity of virus infections, and thus far biogenic, semisynthetic, and synthetic antiviral substances have failed to give satisfactory results. Although
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Publisher Summary This chapter is concerned with virus vaccines and their genetically conditioned markers. For many years, virus vaccines have been in fact the only effective means for reducing the morbidity of virus infections, and thus far biogenic, semisynthetic, and synthetic antiviral substances have failed to give satisfactory results. Although
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Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines
2006There are a large number of tumor antigens, which may either be specific to the tumor or inappropriately expressed or processed (tumor-associated antigen, TAA). Over the last few years, hundreds of new TAAs have been identified. Some of these represent good targets for both passive (antibody based) and active (vaccine based) therapies.
Dalgleish, A, Pandha, H
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Biochemical and Biophysical Research Communications, 2008
Using plasmid-based reverse genetics, we generated a molecularly altered virus, H5N1/PR8-5B19, containing modified HA and NA genes from A/Goose/Guangdong/1/96 (GS/GD/1/96). In the H5N1/PR8-5B19 virus, the HA cleavage site was modified to resemble that of low-pathogenic avian strains and a portion of the NA stalk region was replaced by the ...
Chengjun, Li +9 more
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Using plasmid-based reverse genetics, we generated a molecularly altered virus, H5N1/PR8-5B19, containing modified HA and NA genes from A/Goose/Guangdong/1/96 (GS/GD/1/96). In the H5N1/PR8-5B19 virus, the HA cleavage site was modified to resemble that of low-pathogenic avian strains and a portion of the NA stalk region was replaced by the ...
Chengjun, Li +9 more
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Vaccine, 2005
Some important vaccines, including ones against tuberculosis (Tb) and foot-and-mouth disease (FMD), are not used in many developed countries because there is no simple way to differentiate between vaccine-induced immunity and infection. Eliminating major protein antigens has not succeeded in the cases of Tb, FMD and some other vaccine preparations ...
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Some important vaccines, including ones against tuberculosis (Tb) and foot-and-mouth disease (FMD), are not used in many developed countries because there is no simple way to differentiate between vaccine-induced immunity and infection. Eliminating major protein antigens has not succeeded in the cases of Tb, FMD and some other vaccine preparations ...
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Effect of influenza vaccine on markers of inflammation and lipid profile
Journal of Laboratory and Clinical Medicine, 2005Despite wide use of the influenza vaccine, relatively little is known about its effect on the measurement of inflammatory markers. Because inflammatory markers such as C-reactive protein (CRP) are increasingly being used in conjunction with lipids for the clinical assessment of cardiovascular disease and in epidemiologic studies, we evaluated the ...
Michael Y, Tsai +7 more
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Novel marker vaccines against classical swine fever
Vaccine, 2007Classical swine fever (CSF) is one of the most devastating epizootic diseases of pigs worldwide. For eradication and control purposes, CSF vaccination is an important tool, and efficacious and safe attenuated vaccines have been available for many decades (for example, the C-strain vaccines).
Martin, Beer +3 more
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Using Infection Markers as a Vaccine against Malware Attacks
2012 IEEE International Conference on Green Computing and Communications, 2012Malware is used by criminals for financial gains, espionage and sabotage, and their code and evasion techniques become increasingly complex and sophisticated. This means it takes longer for security researchers to analyse a malware and develop detection and removal routines, increasing the danger of critical systems becoming infected.
André Wichmann, Elmar Gerhards-Padilla
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Laboratory markers for over-attenuation of mumps vaccine virus
Vaccine, 1988The properties of mumps vaccine virus (Leningrad-3 strain) gradually changed upon passaging in quail embryo fibroblasts, the substrate normally used for mumps vaccine production in the USSR. Alterations were extremely noticeable in the over-attenuated (38th passage) virus variant, and involved (a) poor, if any, antibody response in guinea-pigs, (b ...
, Boriskin YuS +4 more
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Experiences with two BHV1 marker vaccines
The Bovine Practitioner, 1997Both marker vaccines tested were deleted vaccines, one had a gG, the other a gE deletion. The gG deleted vaccine was inactivated the gE deleted vaccine had a live and an inactivated form. The object of the trial was to evaluate these vaccines in heifers and calves. Twenty young heifers were used for the inactivated deleted vaccines and 16 four week old
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[Genetic markers of viral vaccines].
Annali Sclavo; rivista di microbiologia e di immunologia, 1981This paper deals with virus vaccines and their genetic markers. In particular we have examined four of the attenuated virus vaccines, now in widespread use, prepared in cell cultures, i.e. poliomyelitis, measles, mumps and rubella. The data reported could be of critical value for the evaluation of the safety and the prophylactic activity of the ...
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