Results 1 to 10 of about 2,319,540 (269)
Application of Janus Particles in Point-of-Care Testing
Biosensors, 2022 Janus particles (JPs), named after the two-faced Roman god, are asymmetric particles with different chemical properties or polarities. JPs have been widely used in the biomedical field in recent years, including as drug carriers for targeted controlled ...
Yuhan Wang +6 more
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Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing
Biosensors, 2022 The development of biosensing platforms has been impressively accelerated by advancements in liquid crystal (LC) technology. High response rate, easy operation, and good stability of the LC droplet-based biosensors are all benefits of the long-range ...
Ruwen Xie +7 more
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Sensors, 2023 Background: The G2019S-LRRK2 gene mutation is a common cause of hereditary Parkinson’s disease (PD), associated with a higher frequency of the postural instability gait difficulty (PIGD) motor phenotype yet with preserved cognition.
Eden Shkury +6 more
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Frontiers in Cell and Developmental Biology, 2021 Alzheimer’s disease (AD), frontotemporal dementia (FTD), and dementia with Lewy bodies (DLB) are the three major neurodegenerative dementias. In this study, we provide evidence that an alteration in extracellular vesicles (EVs) release is common across ...
Antonio Longobardi +12 more
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Marker-of-self becomes marker-of-senescence [PDF]
Blood, 2012 In this issue of Blood , Burger et al provide compelling in vitro evidence that phagocytic uptake of aged human erythrocytes is promoted by the marker of self CD47 in complex with the serum factor thrombospondin-1.[1][1] CD47 is expressed on cells of all types and binds and signals to SIRPα ...
Nisha, Sosale, Dennis E, Discher
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What Makes a Marker a Good Marker? [PDF]
Brain, Behavior and Evolution, 2014 To validate if DCX truly predicts neuron recruitment throughout the canary brain, it should correlate to a high degree with established methods for studying neuron recruitment, such as labeling cells with the mitotic marker 5-bromo-2-deoxyuridine (BrdU).
Vellema, M. +3 more
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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [PDF]
The American Journal of Human Genetics, 2005 Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of human pedigrees.
Abecasis, Gonçalo R. +1 more
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Cells, 2019 Over the last decade, the immune checkpoint blockade targeting the programmed death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis has improved progression-free and overall survival of advanced non-small cell lung cancer (NSCLC) patients.
Vera Kloten +3 more
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Frontiers in Neuroscience, 2021 Alzheimer’s disease (AD) is a pathology characterized by the accumulation in the brain of intracellular and extracellular amyloid-β (Aβ) aggregates, especially of Aβ1–40 and Aβ1–42 peptides.
Guido Domingo +11 more
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Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders
Frontiers in Aging Neuroscience, 2016 The overlap of symptoms between neurodegenerative and psychiatric diseases has been reported. Neuropsychiatric alterations are commonly observed in dementia, especially in the behavioral variant of frontotemporal dementia (bvFTD), which is the most ...
Roberta eZanardini +3 more
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