Results 1 to 10 of about 2,299,844 (269)

Application of Janus Particles in Point-of-Care Testing

Biosensors, 2022
Janus particles (JPs), named after the two-faced Roman god, are asymmetric particles with different chemical properties or polarities. JPs have been widely used in the biomedical field in recent years, including as drug carriers for targeted controlled ...
Yuhan Wang, Peixuan Zhao, Shihao Zhang, Kexiao Zhu, Xiaoya Shangguan, Lishang Liu, Shusheng Zhang   +6 more
doaj   +1 more source

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Biosensors, 2022
The development of biosensing platforms has been impressively accelerated by advancements in liquid crystal (LC) technology. High response rate, easy operation, and good stability of the LC droplet-based biosensors are all benefits of the long-range ...
Ruwen Xie, Na Li, Zunhua Li, Jinrong Chen, Kaixuan Li, Qiang He, Lishang Liu, Shusheng Zhang   +7 more
doaj   +1 more source

Differences in EEG Event-Related Potentials during Dual Task in Parkinson’s Disease Carriers and Non-Carriers of the G2019S-LRRK2 Mutation

Sensors, 2023
Background: The G2019S-LRRK2 gene mutation is a common cause of hereditary Parkinson’s disease (PD), associated with a higher frequency of the postural instability gait difficulty (PIGD) motor phenotype yet with preserved cognition.
Eden Shkury, Shani Danziger-Schragenheim, Zoya Katzir, Yael Ezra, Nir Giladi, Anat Mirelman, Inbal Maidan   +6 more
doaj   +1 more source

Plasma Extracellular Vesicle Size and Concentration Are Altered in Alzheimer’s Disease, Dementia With Lewy Bodies, and Frontotemporal Dementia

Frontiers in Cell and Developmental Biology, 2021
Alzheimer’s disease (AD), frontotemporal dementia (FTD), and dementia with Lewy bodies (DLB) are the three major neurodegenerative dementias. In this study, we provide evidence that an alteration in extracellular vesicles (EVs) release is common across ...
Antonio Longobardi, Luisa Benussi, Roland Nicsanu, Sonia Bellini, Clarissa Ferrari, Claudia Saraceno, Roberta Zanardini, Marcella Catania, Giuseppe Di Fede, Rosanna Squitti, Giuliano Binetti, Giuliano Binetti, Roberta Ghidoni   +12 more
doaj   +1 more source

Circulating Tumor Cell PD-L1 Expression as Biomarker for Therapeutic Efficacy of Immune Checkpoint Inhibition in NSCLC

Cells, 2019
Over the last decade, the immune checkpoint blockade targeting the programmed death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis has improved progression-free and overall survival of advanced non-small cell lung cancer (NSCLC) patients.
Vera Kloten, Rita Lampignano, Thomas Krahn, Thomas Schlange   +3 more
doaj   +1 more source

N-Terminally Truncated and Pyroglutamate-Modified Aβ Forms Are Measurable in Human Cerebrospinal Fluid and Are Potential Markers of Disease Progression in Alzheimer’s Disease

Frontiers in Neuroscience, 2021
Alzheimer’s disease (AD) is a pathology characterized by the accumulation in the brain of intracellular and extracellular amyloid-β (Aβ) aggregates, especially of Aβ1–40 and Aβ1–42 peptides.
Guido Domingo, Luisa Benussi, Claudia Saraceno, Michela Bertuzzi, Roland Nicsanu, Antonio Longobardi, Sonia Bellini, Alfredo Cagnotto, Mario Salmona, Giuliano Binetti, Giuliano Binetti, Roberta Ghidoni   +11 more
doaj   +1 more source

Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders

Frontiers in Aging Neuroscience, 2016
The overlap of symptoms between neurodegenerative and psychiatric diseases has been reported. Neuropsychiatric alterations are commonly observed in dementia, especially in the behavioral variant of frontotemporal dementia (bvFTD), which is the most ...
Roberta eZanardini, Miriam eCiani, Luisa eBenussi, Roberta eGhidoni   +3 more
doaj   +1 more source

Clinical Assessment and Prognostic Evaluation of Tumor Markers in Patients with Gastric Cancer

The International Journal of Biological Markers, 2013
Aim To investigate the relationship between the serum levels of CEA, CA19-9, CA24-2, CA72-4, and AFP in patients with gastric cancer (GC) and their clinicopathological characteristics; to analyze the efficacy of these tumor markers in evaluating the ...
Jing Jiexian, Xu Xiaoqin, Du Lili, Tian Baoguo, Sun Ting, Zhao Xianwen, Han Cunzhi   +6 more
doaj   +1 more source

Cerebrospinal Fluid EV Concentration and Size Are Altered in Alzheimer’s Disease and Dementia with Lewy Bodies

Cells, 2022
Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) represent the three major neurodegenerative dementias characterized by abnormal brain protein accumulation. In this study, we investigated extracellular vesicles (
Antonio Longobardi, Roland Nicsanu, Sonia Bellini, Rosanna Squitti, Marcella Catania, Pietro Tiraboschi, Claudia Saraceno, Clarissa Ferrari, Roberta Zanardini, Giuliano Binetti, Giuseppe Di Fede, Luisa Benussi, Roberta Ghidoni   +12 more
doaj   +1 more source

Clinical Utility of Prostatic Specific Antigen and Prostatic Acid Phosphatase Serum Levels in Monitoring Prostate Cancer

The International Journal of Biological Markers, 1988
We analysed 696 prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum samples by double antibody radioimmunoassay (RIA) I 125 in the follow-up of 122 patients with prostate cancer under treatment.
J. Morote, A. Ruibal, J. Palou, J. A. de Torres, A. Soler-Roselló   +4 more
doaj   +1 more source