Marker-of-self becomes marker-of-senescence [PDF]
In this issue of Blood , Burger et al provide compelling in vitro evidence that phagocytic uptake of aged human erythrocytes is promoted by the marker of self CD47 in complex with the serum factor thrombospondin-1.[1][1] CD47 is expressed on cells of all types and binds and signals to SIRPα ...
Nisha, Sosale, Dennis E, Discher
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What Makes a Marker a Good Marker? [PDF]
To validate if DCX truly predicts neuron recruitment throughout the canary brain, it should correlate to a high degree with established methods for studying neuron recruitment, such as labeling cells with the mitotic marker 5-bromo-2-deoxyuridine (BrdU).
Vellema, M. +3 more
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Inflammatory markers: An Overview
Inflammation is the body’s innate response to injury or insult, including infection, trauma, surgery, burns, and cancer. Certain proteins are released into the bloodstream during inflammation; if their concentrations increase or decrease by at least 25%,
Inflammatory markers: An Overview
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Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Einarsson, Roland +10 more
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Development of microsatellite markers for identifying Brazilian Coffea arabica varieties [PDF]
Microsatellite markers, also known as SSRs (Simple Sequence Repeats), have proved to be excellent tools for identifying variety and determining genetic relationships.
Édila V. de R. Von Pinho +9 more
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Advances in plant gene-targeted and functional markers: a review [PDF]
Public genomic databases have provided new directions for molecular marker development and initiated a shift in the types of PCR-based techniques commonly used in plant science.
Ildikó Varga +22 more
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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [PDF]
Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of human pedigrees.
Abecasis, Gonçalo R. +1 more
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A new and versatile method for the successful conversion of AFLP-TM markers into simple single locus markers [PDF]
Genetic markers can efficiently be obtained by using amplified fragment length polymorphism (AFLP) fingerprinting because no prior information on DNA sequence is required.
Brugmans, B.W. +4 more
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Genome- and transcriptome-assisted development of nuclear insertion/deletion markers for Calanus species (Copepoda: Calanoida) identification [PDF]
Copepods of the genus Calanus are key zooplankton species in temperate to arctic marine ecosystems. Despite their ecological importance, species identification remains challenging.
Poortvliet, Marloes +29 more
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Clinical usefulness of cancer markers in primary breast cancer [PDF]
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Verring, A. +3 more
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