Results 11 to 20 of about 2,299,844 (269)
Marker-of-self becomes marker-of-senescence [PDF]
Blood, 2012 In this issue of Blood , Burger et al provide compelling in vitro evidence that phagocytic uptake of aged human erythrocytes is promoted by the marker of self CD47 in complex with the serum factor thrombospondin-1.[1][1] CD47 is expressed on cells of all types and binds and signals to SIRPα ...
Nisha, Sosale, Dennis E, Discher
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What Makes a Marker a Good Marker? [PDF]
Brain, Behavior and Evolution, 2014 To validate if DCX truly predicts neuron recruitment throughout the canary brain, it should correlate to a high degree with established methods for studying neuron recruitment, such as labeling cells with the mitotic marker 5-bromo-2-deoxyuridine (BrdU).
Vellema, M. +3 more
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Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [PDF]
The American Journal of Human Genetics, 2005 Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of human pedigrees.
Abecasis, Gonçalo R. +1 more
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Accuracy of marker-assisted selection with single markers and marker haplotypes in cattle
Genetical Research, 2007 SummaryA key question for the implementation of marker-assisted selection (MAS) using markers in linkage disequilibrium with quantitative trait loci (QTLs) is how many markers surrounding each QTL should be used to ensure the marker or marker haplotypes are in sufficient linkage disequilibrium (LD) with the QTL. In this paper we compare the accuracy of
Hayes, B J. +5 more
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Imaging Markers in Genetic Forms of Parkinson’s Disease
Brain Sciences, 2023 Parkinson’s disease (PD) is a complex neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rigidity, and resting tremor.
Amgad Droby, Avner Thaler, Anat Mirelman
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Conjugated Polymeric Materials in Biological Imaging and Cancer Therapy
Molecules, 2023 Conjugated polymers (CPs) have attracted much attention in the fields of chemistry, medicine, life science, and material science. Researchers have carried out a series of innovative researches and have made significant research progress regarding the ...
Qinbin Zheng +7 more
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Frontiers in Bioengineering and Biotechnology, 2021 As a widely used anticancer drug, doxorubicin (DOX) could induce cell death mainly via interfering with DNA activity; thus, DOX could perform therapeutic effects mainly in the cell nucleus.
Xinyue Song +8 more
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Serum CA 15.3, CEA and ESR Patterns in Breast Cancer
The International Journal of Biological Markers, 1997 Serum CA 15.3, CEA and ESR were longitudinally determined in 298 patients with breast cancer during postsurgical follow-up and/or therapy. Observation lasted until the death of the patient or at least for three years.
M. Rubach +3 more
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Frontiers in Neuroscience, 2019 Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis,
Miriam Ciani +4 more
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Nanomaterials, 2023 Tobacco bacterial wilt is a serious disease caused by the soil-borne bacterium Ralstonia solanacearum (R. solanacearum). Herein, a rapid and purification-free α-hemolysin (α-HL) nanopore-sensing strategy based on polymerase chain reaction (PCR) and ...
Ying Wang +5 more
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