Results 11 to 20 of about 2,319,540 (269)

Clinical Assessment and Prognostic Evaluation of Tumor Markers in Patients with Gastric Cancer

The International Journal of Biological Markers, 2013
Aim To investigate the relationship between the serum levels of CEA, CA19-9, CA24-2, CA72-4, and AFP in patients with gastric cancer (GC) and their clinicopathological characteristics; to analyze the efficacy of these tumor markers in evaluating the ...
Jing Jiexian, Xu Xiaoqin, Du Lili, Tian Baoguo, Sun Ting, Zhao Xianwen, Han Cunzhi   +6 more
doaj   +1 more source

Cerebrospinal Fluid EV Concentration and Size Are Altered in Alzheimer’s Disease and Dementia with Lewy Bodies

Cells, 2022
Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) represent the three major neurodegenerative dementias characterized by abnormal brain protein accumulation. In this study, we investigated extracellular vesicles (
Antonio Longobardi, Roland Nicsanu, Sonia Bellini, Rosanna Squitti, Marcella Catania, Pietro Tiraboschi, Claudia Saraceno, Clarissa Ferrari, Roberta Zanardini, Giuliano Binetti, Giuseppe Di Fede, Luisa Benussi, Roberta Ghidoni   +12 more
doaj   +1 more source

Clinical Utility of Prostatic Specific Antigen and Prostatic Acid Phosphatase Serum Levels in Monitoring Prostate Cancer

The International Journal of Biological Markers, 1988
We analysed 696 prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum samples by double antibody radioimmunoassay (RIA) I 125 in the follow-up of 122 patients with prostate cancer under treatment.
J. Morote, A. Ruibal, J. Palou, J. A. de Torres, A. Soler-Roselló   +4 more
doaj   +1 more source

Imaging Markers in Genetic Forms of Parkinson’s Disease

Brain Sciences, 2023
Parkinson’s disease (PD) is a complex neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rigidity, and resting tremor.
Amgad Droby, Avner Thaler, Anat Mirelman
doaj   +1 more source

Accuracy of marker-assisted selection with single markers and marker haplotypes in cattle

Genetical Research, 2007
SummaryA key question for the implementation of marker-assisted selection (MAS) using markers in linkage disequilibrium with quantitative trait loci (QTLs) is how many markers surrounding each QTL should be used to ensure the marker or marker haplotypes are in sufficient linkage disequilibrium (LD) with the QTL. In this paper we compare the accuracy of
Hayes, B J., Goddard, M. E., Sethuraman, L., Chamberlain, A J., McPartlan, H., Macleod, I.   +5 more
openaire   +5 more sources

Conjugated Polymeric Materials in Biological Imaging and Cancer Therapy

Molecules, 2023
Conjugated polymers (CPs) have attracted much attention in the fields of chemistry, medicine, life science, and material science. Researchers have carried out a series of innovative researches and have made significant research progress regarding the ...
Qinbin Zheng, Zhuli Duan, Ying Zhang, Xinqi Huang, Xuefan Xiong, Ang Zhang, Kaiwen Chang, Qiong Li   +7 more
doaj   +1 more source

Aptamer Functionalized Upconversion Nanotheranostic Agent With Nuclear Targeting as the Highly Localized Drug-Delivery System of Doxorubicin

Frontiers in Bioengineering and Biotechnology, 2021
As a widely used anticancer drug, doxorubicin (DOX) could induce cell death mainly via interfering with DNA activity; thus, DOX could perform therapeutic effects mainly in the cell nucleus.
Xinyue Song, Xinyue Song, Tao Yan, Feng Tian, Fengyan Li, Linlin Ren, Qiong Li, Qiong Li, Shusheng Zhang   +8 more
doaj   +1 more source

Genome Wide Association Study and Next Generation Sequencing: A Glimmer of Light Toward New Possible Horizons in Frontotemporal Dementia Research

Frontiers in Neuroscience, 2019
Frontotemporal Dementia (FTD) is a focal neurodegenerative disease, with a strong genetic background, that causes early onset dementia. The present knowledge about the risk loci and causative mutations of FTD mainly derives from genetic linkage analysis,
Miriam Ciani, Miriam Ciani, Luisa Benussi, Cristian Bonvicini, Roberta Ghidoni   +4 more
doaj   +1 more source

Detection of Tobacco Bacterial Wilt Caused by Ralstonia solanacearum by Combining Polymerase Chain Reaction with an α-Hemolysin Nanopore

Nanomaterials, 2023
Tobacco bacterial wilt is a serious disease caused by the soil-borne bacterium Ralstonia solanacearum (R. solanacearum). Herein, a rapid and purification-free α-hemolysin (α-HL) nanopore-sensing strategy based on polymerase chain reaction (PCR) and ...
Ying Wang, Yusen Li, Xin Zhou, Wenna Zhang, Shusheng Zhang, Dongmei Xi   +5 more
doaj   +1 more source

Serum CA 15.3, CEA and ESR Patterns in Breast Cancer

The International Journal of Biological Markers, 1997
Serum CA 15.3, CEA and ESR were longitudinally determined in 298 patients with breast cancer during postsurgical follow-up and/or therapy. Observation lasted until the death of the patient or at least for three years.
M. Rubach, J.J. Szymendera, J. Kamińska, M. Kowalska   +3 more
doaj   +1 more source