Results 21 to 30 of about 4,741,522 (298)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Trees, Forests and PeopleIn response to a disease outbreak affecting an iconic ecosystem, restricting recreational access emerges as a crucial strategy to control disease spread, despite significant social and economic impacts.
Stefania Mattea, Juan J. Monge
doaj +1 more source
The influence of emotions and personal values on packaging preference decisions [PDF]
The Retail and Marketing Review, 2014 The importance of emotions and personal values for consumer decision-making is well documented. This article aims to provide additional insight into the relative influence of emotions and personal values in packaging preference decisions.
JPR Joubert, J Poalses
doaj
East Midlands life and work survey 2003: themed summary report - business start up [PDF]
, 2004 Themed report from the 2003 East Midlands regional household survey, 'The Life and Work Survey', undertaken to inform a range of partner organisations, including emda and the Learning and Skills Council.
Market Research UK Ltd.
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
East Midlands life and work survey 2003: technical report [PDF]
, 2003 Technical report for the 2003 East Midlands regional household survey, 'The Life and Work Survey', undertaken to inform a range of partner organisations, including emda and the Learning and Skills Council. A core sample of 14,000 was achieved across the
Market Research UK Ltd.
core
Conducting market research using the internet: The case of Xenon laboratories [PDF]
, 2004 The way market research is conducted has changed dramatically over the past 30 years, as a result of both the development of the prevailing view of best practice and the state of technology available to researchers.
Blackman, ID, Lockett, A
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Is it Easier to Escape from Low Pay in Urban Areas? Evidence from the UK [PDF]
, 2004 In this paper we compare periods of low pay employment between urban and rural areas in the UK. Using the British Household Panel Survey, we estimate the probability that a period of low pay employment will end allowing for a number of possible outcomes,
Centre for European Labour Market Research +3 more
core
Managing in an economic crisis: The role of market orientation in an international law firm [PDF]
, 2013 This research paper contributes to the understanding of the relationship between market orientation and performance in the context of a law firm during a time of economic crisis.
Appiah-Adu +66 more
core +1 more source