Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
CONDITIONS FOR APPLYING A MARKETING APPROACH BY BULGARIAN VEGETABLE PRODUCERS
The purpose of the article is to outline the prerequisites for the implementation of marketing activities by Bulgarian vegetable producers. Improving the effectiveness of marketing activities can be achieved only if the necessary prerequisites for this ...
Teodor Radev
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
The interface between transactional and relational orientation in small service firm's marketing behaviour [PDF]
This paper presents and discusses findings of a cross-country study of small service firm marketing behavior. These findings demonstrate that small service firms are flexible in the marketing approaches that they adopt.
Hultman, C., Shaw, E.
core
Crowdsourcing Application in Marketing Activities
AbstractActive deployment of information communication technologies between consumers’ enables them contribute actively to various business activities. A crowdsourcing phenomenon is observed recently from perspectives ranging from users involvement in company's communication activities to various crowdfunding models.
Elena Vitkauskaite, Rimantas Gatautis
openaire +2 more sources
A strategic market game with active bankruptcy [PDF]
The authors study a mathematical model of a macroeconomic system including one nondurable commodity, countably many time periods and a continuum of agents. It is a stochastic model, for individual agents' endowments fluctuate in a random fashion from period to period.
John Geanakoplos+3 more
openaire +3 more sources
Analysis of organization and implementation of marketing on example of Serbian organic food producers [PDF]
Adequate application of marketing activities determines the competitiveness of organic food producers and creates the conditions for a faster development of the organic market.
Vehapi Semir, Šabotić Zenaida
doaj
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts+8 more
wiley +1 more source
Selecting an IMC Career: Influences, Choices and Destinations [PDF]
Integrated marketing communication incorporates both customer and non-customer stakeholder groups. While the literature commonly refers to this distinction as marketing communication and corporate communication, respectively, and practitioners accept the
Larkin, Ingrid+2 more
core +1 more source
Entrepreneurial marketing : a historical perspective on development and practice [PDF]
Entrepreneurial marketing is a term which is receiving increasing use. It essentially encompasses two very distinct areas of management: marketing and entrepreneurship.
Collinson, E.M., Shaw, E.
core +1 more source