Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
The ultrathin (2.5 nm) MXene film self‐assembled at liquid interfaces breaks the trade‐off between transparency (82.5 %) and photothermal conversion effect (DT∼25.1°C ± 2.9 °C) under 100 mW cm−2. After encapsulated by a slippery surface with low adhesion, this transparent film can be applied in smart windows, eyewear, and optical sensors to autonomous ...
Xiao Han +6 more
wiley +1 more source
Plant-Based Meat Analogues and Consumer Interest in 3D-Printed Products: A Mini-Review. [PDF]
Miller O, Scarlett CJ, Akanbi TO.
europepmc +1 more source
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Baru Almond Beverage (<i>Baruccino</i>) with Different Sweeteners: Nutritional and Physical Properties and Exploration of Sensory and Non-Sensory Perceptions. [PDF]
Batista LF +5 more
europepmc +1 more source
"Crunch my Heart! It Falls for You: Re-theorizing Chocolate Gift-Giving as Carnal Singularity Across Language Contexts [PDF]
Bettany, S. +5 more
core
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Vineyard Location Impact on the Composition and Quality of Wines from International and Native Varieties Grown in Drama, Greece. [PDF]
Skendi A +5 more
europepmc +1 more source
Polyelectrolyte Design Principles for Electrophoretic Drug Delivery
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo +8 more
wiley +1 more source
Sensory Attributes and Chemical Composition: The Case of Three Monofloral Honey Types from Algeria. [PDF]
Nakib R +7 more
europepmc +1 more source

