Results 31 to 40 of about 14,128,135 (294)

Evaluation of Markov Models with Discontinuities [PDF]

open access: yesMedical Decision Making, 2019
Background. Several methods, such as the half-cycle correction and the life-table method, were developed to attenuate the error introduced in Markov models by the discretization of time. Elbasha and Chhatwal have proposed alternative “corrections” based on numerical integration techniques.
Jorge Pérez-Martín   +2 more
openaire   +3 more sources

Modeling stochastic gene expression: From Markov to non-Markov models

open access: yesMathematical Biosciences and Engineering, 2020
Gene expression is an inherently noisy process due to low copy numbers of mRNA or protein. The involved reaction events may happen in a Markov fashion but also in a non-Markov manner, depending on waiting-time distributions for the occurrence of reaction events.
Zhenquan Zhang   +4 more
openaire   +4 more sources

Cascaded Markov Models [PDF]

open access: yesProceedings of the ninth conference on European chapter of the Association for Computational Linguistics -, 1999
This paper presents a new approach to partial parsing of context-free structures. The approach is based on Markov Models. Each layer of the resulting structure is represented by its own Markov Model, and output of a lower layer is passed as input to the next higher layer. An empirical evaluation of the method yields very good results for NP/PP chunking
openaire   +4 more sources

Modeling the progression of NAFLD: a multi-state Markov approach based on BMI classification in the Chinese population [PDF]

open access: yesExploration of Endocrine and Metabolic Diseases
Aim: To investigate the natural history and progression of non-alcoholic fatty liver disease (NAFLD) in Chinese adults using a community-based longitudinal cohort. Methods: We analyzed data from 24,893 adults in the Beijing Health Management Cohort (2016–
Jianmin Tang   +8 more
doaj   +1 more source

Sintilimab Plus Bevacizumab Biosimilar Versus Sorafenib as First-Line Treatment for Unresectable Hepatocellular Carcinoma: A Cost-Effectiveness Analysis

open access: yesFrontiers in Pharmacology, 2022
Objective: The ORIENT-32 clinical trial revealed that sintilimab plus bevacizumab biosimilar significantly improved the median progression-free survival and median overall survival (OS) compared with sorafenib.
Ye Peng   +10 more
doaj   +1 more source

USING PHARMACOECONOMIC MODELLING TO DETERMINE VALUE-BASED PRICING FOR NEW MEDICINES

open access: yesКубанский научный медицинский вестник, 2017
Purpose: to carry out pharmacoeconomic modeling for an early economic evaluation of the generic pegylated liposomal doxorubicin (PLD) drug.Materials and methods: a Markov model and Decision tree model were developed to simulate and to compare the costs ...
I. S. KRYSANOV   +3 more
doaj   +1 more source

Hodgkin’s Lymphoma: Analysis Results of Volgograd Regional Registry

open access: yesКлиническая онкогематология, 2019
Background. The present paper discusses feasibility of first- and second-line therapies as well as the significance of different risk factors in the population of all patients with newly diagnosed Hodgkin’s lymphomas (HL) in a 14-year period based on the
Kamil Daniyalovich Kaplanov   +7 more
doaj   +1 more source

Value-based approach to blood pressure telemonitoring and remote counseling in hypertensive patients

open access: yesBlood Pressure, 2021
Purpose Blood pressure telemonitoring and remote counselling (BPTM) improves blood pressure (BP) control in patients with hypertension (HTN). Studies assessing the efficacy of BPTM from a value-based perspective are lacking.
Mikhail V. Ionov   +7 more
doaj   +1 more source

Cost-Effectiveness of Triple Therapy with Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate versus Dual Therapies in Moderate-to-Very Severe Chronic Obstructive Pulmonary Disease: United Kingdom Analysis Using the ETHOS Study

open access: yesInternational Journal of COPD, 2022
Enrico de Nigris,1 Catrin Treharne,2 Nick Brighton,2 Ulf Holmgren,3 Andrew Walker,4 John Haughney5 1Formerly of Global Product and Portfolio Strategy, AstraZeneca, Cambridge, UK; 2Formerly of Health Economic Modelling, Regulatory and Access, Parexel ...
de Nigris E   +5 more
doaj  

Cost-effectiveness analysis of influenza vaccination among the elderly in Qingdao city

open access: yesZhongguo gonggong weisheng
ObjectiveTo evaluate the cost-effectiveness of different influenza vaccination rates among the elderly population aged 65 years and above in Qingdao city.
Jinru LI   +6 more
doaj   +1 more source

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