Results 31 to 40 of about 254,480 (307)
Exploratory search during directed navigation in C. elegans and Drosophila larva
eLife, 2017 Many organisms—from bacteria to nematodes to insect larvae—navigate their environments by biasing random movements. In these organisms, navigation in isotropic environments can be characterized as an essentially diffusive and undirected process.
Mason Klein +5 more
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Modeling stochastic gene expression: From Markov to non-Markov models
Mathematical Biosciences and Engineering, 2020 Gene expression is an inherently noisy process due to low copy numbers of mRNA or protein. The involved reaction events may happen in a Markov fashion but also in a non-Markov manner, depending on waiting-time distributions for the occurrence of reaction events.
Zhenquan Zhang +4 more
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Frontiers in Pharmacology, 2022 Objective: The ORIENT-32 clinical trial revealed that sintilimab plus bevacizumab biosimilar significantly improved the median progression-free survival and median overall survival (OS) compared with sorafenib.
Ye Peng +10 more
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Modeling the progression of NAFLD: a multi-state Markov approach based on BMI classification in the Chinese population [PDF]
Exploration of Endocrine and Metabolic DiseasesAim: To investigate the natural history and progression of non-alcoholic fatty liver disease (NAFLD) in Chinese adults using a community-based longitudinal cohort. Methods: We analyzed data from 24,893 adults in the Beijing Health Management Cohort (2016–
Jianmin Tang +8 more
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A coupled hidden Markov model for disease interactions [PDF]
, 2012 To investigate interactions between parasite species in a host, a population of field voles was studied longitudinally, with presence or absence of six different parasites measured repeatedly.
Telfer, S.E. +11 more
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USING PHARMACOECONOMIC MODELLING TO DETERMINE VALUE-BASED PRICING FOR NEW MEDICINES
Кубанский научный медицинский вестник, 2017 Purpose: to carry out pharmacoeconomic modeling for an early economic evaluation of the generic pegylated liposomal doxorubicin (PLD) drug.Materials and methods: a Markov model and Decision tree model were developed to simulate and to compare the costs ...
I. S. KRYSANOV +3 more
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Value-based approach to blood pressure telemonitoring and remote counseling in hypertensive patients
Blood Pressure, 2021 Purpose Blood pressure telemonitoring and remote counselling (BPTM) improves blood pressure (BP) control in patients with hypertension (HTN). Studies assessing the efficacy of BPTM from a value-based perspective are lacking.
Mikhail V. Ionov +7 more
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Hodgkin’s Lymphoma: Analysis Results of Volgograd Regional Registry
Клиническая онкогематология, 2019 Background. The present paper discusses feasibility of first- and second-line therapies as well as the significance of different risk factors in the population of all patients with newly diagnosed Hodgkin’s lymphomas (HL) in a 14-year period based on the
Kamil Daniyalovich Kaplanov +7 more
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International Journal of COPD, 2022 Enrico de Nigris,1 Catrin Treharne,2 Nick Brighton,2 Ulf Holmgren,3 Andrew Walker,4 John Haughney5 1Formerly of Global Product and Portfolio Strategy, AstraZeneca, Cambridge, UK; 2Formerly of Health Economic Modelling, Regulatory and Access, Parexel ...
de Nigris E +5 more
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