Results 51 to 60 of about 10,800,365 (307)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Modelling the profitability of credit cards by Markov decision processes

open access: yes, 2009
This paper derives a model for the profitability of credit cards, which allow lenders to find the optimal dynamic credit limit policy. The model is a Markov decision process, where the states of the system are based on the borrower's behavioural score ...
Thomas, Lyn C., So, Mee Chi
core   +1 more source

CHARACTERISTICS OF A RANDOM PROCESS IN PROBLEMS OF COMPUTER MODELING AND ENTROPY ANALYSIS OF SYSTEMS

open access: yesНадежность и качество сложных систем, 2021
Background. The present time is characterized by the intensive development of the means of informatization of society, the widespread introduction of digital systems and computer technologies with support for managerial decision-making.
A.V. Poltavskiy   +2 more
doaj   +1 more source

Charting Endocrine Progenitors Across Species and Organs

open access: yesAdvanced Science, EarlyView.
Endocrine progenitors give rise to the hormone‐producing cells of the pancreas and intestine. Using single‐cell multiomics and proteomics, this study compares these progenitors across species, systems, and organs, mapping the conserved and species‐specific gene regulatory networks that guide their formation.
Changying Jing   +21 more
wiley   +1 more source

Investigation of insertion tableau evolution in the Robinson-Schensted-Knuth correspondence

open access: yesDiscrete and Continuous Models and Applied Computational Science, 2019
Robinson-Schensted-Knuth (RSK) correspondence occurs in different contexts of algebra and combinatorics. Recently, this topic has been actively investigated by many researchers.
Vasilii S. Duzhin
doaj   +1 more source

Stochastic monotonicity and duality for one-dimensional Markov processes [PDF]

open access: yes, 2011
The theory of monotonicity and duality is developed for general one-dimensional Feller processes, extending the approach from [11]. Moreover it is shown that local monotonicity conditions (conditions on the Lévy kernel) are sufficient to prove the well-
Kolokoltsov, V. N. (Vasiliĭ Nikitich)
core   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

A Novel System Reliability Modeling of Hardware, Software, and Interactions of Hardware and Software

open access: yesMathematics, 2019
In the past few decades, a great number of hardware and software reliability models have been proposed to address hardware failures in hardware subsystems and software failures in software subsystems, respectively.
Mengmeng Zhu, Hoang Pham
doaj   +1 more source

Bayesian selection of Markov models for symbol sequences: application to microsaccadic eye movements. [PDF]

open access: yesPLoS ONE, 2012
Complex biological dynamics often generate sequences of discrete events which can be described as a Markov process. The order of the underlying Markovian stochastic process is fundamental for characterizing statistical dependencies within sequences.
Mario Bettenbühl   +3 more
doaj   +1 more source

The Compositional Construction of Markov Processes [PDF]

open access: yesApplied Categorical Structures, 2010
We describe an algebra for composing automata in which the actions have probabilities. We illustrate by showing how to calculate the probability of reaching deadlock in k steps in a model of the classical Dining Philosopher problem, and show, using the Perron-Frobenius Theorem, that this probability tends to 1 as k tends to infinity.
Luisa de Francesco Albasini   +2 more
openaire   +5 more sources

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