Results 51 to 60 of about 113,981 (269)

Interaction of Markov processes

Advances in Mathematics, 1970
For a gentle approach to the problems connected with interacting Markov processes we review first what is known in the absence of interaction. For simplicity let S be a countable (or finite) set, and consider a countable (or finite if S is finite) collection of independent Markov processes on S,with common transition function P t (x,y), x, y ∈ S. It is
openaire   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Robustness and Convergence of a Stochastic Deterioration Prediction Model for Tunnel Lighting Facilities: A Japanese Case Study Based on Systematized Expert Knowledge and Large-Scale Monte Carlo Simulation

Applied Sciences
Much of Japan’s social infrastructure was concentrated during the period of rapid economic growth around the 1970s and is now facing the serious problem of simultaneous aging.
Yasuko Kawahata, Noriaki Maeda, Shunsuke Hatadani   +2 more
doaj   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

Advanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang, Xiaoqing Gong, Shukai Gu, Jing Li, Bo Liu, Yanan Tian, Qianqian Zhang, Xiaojun Yao, Huanxiang Liu   +8 more
wiley   +1 more source

CHARACTERISTICS OF A RANDOM PROCESS IN PROBLEMS OF COMPUTER MODELING AND ENTROPY ANALYSIS OF SYSTEMS

Надежность и качество сложных систем, 2021
Background. The present time is characterized by the intensive development of the means of informatization of society, the widespread introduction of digital systems and computer technologies with support for managerial decision-making.
A.V. Poltavskiy, A.A. Tyugashev, N.K. Yurkov   +2 more
doaj   +1 more source

Bayesian selection of Markov models for symbol sequences: application to microsaccadic eye movements. [PDF]

PLoS ONE, 2012
Complex biological dynamics often generate sequences of discrete events which can be described as a Markov process. The order of the underlying Markovian stochastic process is fundamental for characterizing statistical dependencies within sequences.
Mario Bettenbühl, Marco Rusconi, Ralf Engbert, Matthias Holschneider   +3 more
doaj   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Investigation of insertion tableau evolution in the Robinson-Schensted-Knuth correspondence

Discrete and Continuous Models and Applied Computational Science, 2019
Robinson-Schensted-Knuth (RSK) correspondence occurs in different contexts of algebra and combinatorics. Recently, this topic has been actively investigated by many researchers.
Vasilii S. Duzhin
doaj   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source