Results 141 to 150 of about 86,980 (313)

When Dihedral Angles Mask Denticity in Molecular Conductance

open access: yesChemPhysChem, EarlyView.
This study tests whether higher molecule–electrode denticity increases conductance in single‐molecule junctions. Using nonequilibrium Green's function technique in conjunction with density functional theory simulations and mechanically controlled break‐junction experiments on a tetradentate N‐heterohexacene, it is found that conductance depends mainly ...
Kevin Batzinger   +8 more
wiley   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin   +6 more
wiley   +1 more source

TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data

open access: yesCytometry Part A, EarlyView.
TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou   +2 more
wiley   +1 more source

Patterns of understorey bird diversity across Amazonian forests: survey effort and range maps predict local species richness

open access: yesEcography, EarlyView.
Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga   +14 more
wiley   +1 more source

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