Results 131 to 140 of about 1,176,059 (339)
Constraints on the shallow elastic and anelastic structure of Mars from InSight seismic data
Nature Geoscience, 2020 P. Lognonné, P. Lognonné, W. Banerdt, W. Pike, D. Giardini, U. Christensen, R. Garcia, T. Kawamura, S. Kedar, B. Knapmeyer‐Endrun, L. Margerin, F. Nimmo, M. Panning, B. Tauzin, John‐Robert Scholz, Daniele Antonangeli, S. Barkaoui, É. Beucler, F. Bissig, N. Brinkman, M. Calvet, S. Ceylan, C. Charalambous, P. Davis, M. Driel, M. Drilleau, L. Fayon, R. Joshi, B. Kenda, Amir Khan, Amir Khan, M. Knapmeyer, V. Lekić, J. McClean, D. Mimoun, N. Murdoch, Lu Pan, C. Perrin, B. Pinot, L. Pou, S. Menina, Sebastien Rodriguez, Sebastien Rodriguez, C. Schmelzbach, N. Schmerr, D. Sollberger, A. Spiga, A. Spiga, S. Stähler, A. Stott, É. Stutzmann, S. Tharimena, R. Widmer-Schnidrig, Fredrik Andersson, V. Ansan, C. Beghein, M. Böse, E. Bozdağ, J. Clinton, I. Daubar, P. Delage, N. Fuji, M. Golombek, M. Grott, A. Horleston, K. Hurst, J. Irving, A. Jacob, J. Knollenberg, S. Krasner, C. Krause, R. Lorenz, C. Michaut, C. Michaut, R. Myhill, T. Nissen‐Meyer, J. T. Pierick, A. Plesa, C. Quantin-Nataf, J. Robertsson, L. Rochas, M. Schimmel, S. Smrekar, T. Spohn, N. Teanby, J. Tromp, J. Vallade, N. Verdier, C. Vrettos, R. Weber, D. Banfield, E. Barrett, M. Bierwirth, S. Calcutt, N. Compaire, C. L. Johnson, C. L. Johnson, D. Mance, F. Euchner, L. Kerjean, G. Mainsant, A. Mocquet, J. A. R. Manfredi, G. Pont, P. Laudet, T. Nebut, S. D. Raucourt, O. Robert, Christopher T. Russell, A. Sylvestre-baron, S. Tillier, T. Warren, M. Wieczorek, C. Yana, P. Zweifel +114 moresemanticscholar +1 more sourceAssociation of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim +11 morewiley +1 more sourceThe atmosphere of Mars as observed by InSight
Nature Geoscience, 2020 D. Banfield, A. Spiga, C. Newman, F. Forget, M. Lemmon, R. Lorenz, N. Murdoch, D. Viúdez‐Moreiras, J. Pla‐García, R. F. Garcia, P. Lognonné, Ö. Karatekin, C. Perrin, L. Martire, N. Teanby, B. Hove, Justin N. Maki, B. Kenda, Nils T. Mueller, S. Rodriguez, T. Kawamura, J. McClean, A. Stott, C. Charalambous, E. Millour, Catherine L. Johnson, A. Mittelholz, A. Määttänen, Stephen R. Lewis, J. Clinton, S. Stähler, S. Ceylan, D. Giardini, T. Warren, W. T. Pike, I. Daubar, M. Golombek, L. Rolland, R. Widmer-Schnidrig, D. Mimoun, É. Beucler, A. Jacob, A. Lucas, M. Baker, V. Ansan, K. Hurst, L. Mora-Sotomayor, S. Navarro, J. Torres, A. Lepinette, A. Molina, Mercedes Marin-Jimenez, J. Gómez-Elvira, V. Peinado, J. Rodríguez-Manfredi, B. Carcich, S. Sackett, Christopher T. Russell, T. Spohn, S. Smrekar, W. Banerdt +60 moresemanticscholar +1 more sourceITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena +9 morewiley +1 more sourceExploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez +13 morewiley +1 more sourceβ‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón +8 morewiley +1 more source
