Results 131 to 140 of about 562,958 (314)
Mars' nordligste feltgeolog - Phoenix Mars Lander
GeologiskNyt, 2008 <div>Lastet med mikroskoper, ovne, en skovl, en vejrstation og et mindre kemilaboratorium er feltarbejdet gået igang for Phoenix. For første gang kortlægges det polare klima ved Mars’ nordpol, og Phoenix har afsløret is i 5 cm’s ...
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
2009 e-MARS EVALUATION REPORT PRESENTATION (3 of 3)
, 2009 Following various modifications made to the e-MARS form, notably following the restructuring of CERN, three information sessions have been organized for all staff ...
Ariana Morris, Gabriele Thiede
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Mars Historical and Ethical Context : Past, Present, and Imagination
Mars has long been a source of inspiration, imagination and, lately, aspiration for many. It has generated a breadth of beliefs and ideas, as well as hope for a bright future there.
Capova, Klara-Anna +12 more
core +1 more source
MARS: Colour x-rays of people [PDF]
, 2008 Goal: To produce a poster for New Zealand high schools explaining a new form of medical imaging. Background: The MARS team has developed an novel x-ray scanner which produces three dimensional spectroscopic x-ray images of small animals and ...
MARS-CT Team, Butler, A.P.H.
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source