Results 201 to 210 of about 52,598 (262)

Smartphone Apps for Cannabis Cessation: Quality Assessment and Content Analysis. [PDF]

JMIR Mhealth Uhealth
Seth S, Kushwaha S, Prashad R, Chaiton M.   +3 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Identification of an uncharacterized gene as a mitochondrial methionine tRNA synthetase in Caenorhabditis elegans. [PDF]

G3 (Bethesda)
Thapa BV, Das M, Taylor DI, Held JP, Patel MR.   +4 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Virtual reality-based mindfulness applications: a commercial health app review. [PDF]

BMJ Health Care Inform
Ghosal S, Zhang M, Bogosian A, Marsh E, Edginton T, Stanmore E, O'Connor S.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Extreme Arabian environments and their microbiomes: new frontiers for astrobiology and biosignature discovery. [PDF]

Extremophiles
Schultz J, García-Martínez PM, Altalhi S, Kontis N, Dos Santos A, Rosado AS.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Understanding Medication Adherence and Glycaemic Level in People With Type 2 Diabetes Across Countries: A Cross-Sectional and Longitudinal Analysis of Medication Beliefs, Illness Perceptions, Resistance to Illness and Mood. [PDF]

Endocrinol Diabetes Metab
Teo V, Weinman J, Yap KZ, Lopez SE, Hodgkinson A, Chamley M.   +5 more
europepmc   +1 more source

Addendum: Evaluating Characteristics and Quality of Mental Health Apps Available in App Stores for Indian Users: Systematic App Search and Review. [PDF]

JMIR Mhealth Uhealth
Mehrotra S, Tripathi R, Sengupta P, Karishiddimath A, Francis A, Sharma P, Sudhir P, Srikanth TK, Rao G, Sagar R.   +9 more
europepmc   +1 more source