Results 201 to 210 of about 970,728 (295)

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Telerehabilitation Following Stroke: Development of Training Content and Evaluation of an App-Based Training Program. [PDF]

JMIR Rehabil Assist Technol
Ziller C, Gäumann S, Lüscher S, Paulissen N, Behrendt F, Suica Z, Crüts B, Gamerschlag L, Parmar K, Gerth HU, Bonati LH, Schuster-Amft C.   +11 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Multilayer perceptron modeling of health literacy and medication adherence determinants in Arab patients with cardiometabolic disease: the role of quality of life, eating behaviors, and physical activity. [PDF]

BMC Res Notes
Alharbi HF, Al Mutair A, Daniyal M.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Adherence to vitamin and dietary supplement intake in fertility and pregnancy care: insights into knowledge, information satisfaction, and formulation variability. [PDF]

Arch Gynecol Obstet
Breuste NJ, Schippert C, von Versen-Höynck F.   +2 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Clinical Usability of Exercise Prescription Apps for Professional Use: Systematic Review and Multidimensional Evaluation.

JMIR Mhealth Uhealth
Wu CH, Chang CN, Chang CF, Lin MH, Chen HY, Chen YC.   +5 more
europepmc   +1 more source

Ecological Niche Modeling of the Narrow-Range Endangered Endemic <i>Lepidium olgae</i> in Uzbekistan. [PDF]

Plants (Basel)
Abulfayzov K, Khabibullaev B, Shomurodov K, Beshko N, Sullieva S, Li Y, Fan L.   +6 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source