Results 221 to 230 of about 151,951 (312)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Ultrastructure of <i>Serratia liquefaciens</i> Grown at 7 mbar Under Simulated Martian Conditions. [PDF]

Microorganisms
Schuerger AC, Kelley KL.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Variant-specific interaction of kinectin 1 with the multi-tRNA synthetase complex regulates ER sheet organization. [PDF]

iScience
Hosogane M, Siao SY, Hatano A, Huang X, Shichino Y, Watanabe Y, Iwasaki S, Matsumoto M, Nakayama K.   +8 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Precipitation induced by explosive volcanism on Mars and its implications for unexpected equatorial ice. [PDF]

Nat Commun
Hamid SS, Kerber L, Clarke AB.
europepmc   +1 more source

Explore Moon to Mars: Moon Lights the Way - Inspiring the Next Generation

, 2019
Bethanne Hull
openalex   +1 more source

ANALYSIS OF DEIXIS IN "DIE WITH A SMILE" BY BRUNO MARS AND LADY GAGA

Zahra Bil Nazzary, Pipit Rahayu, Eripuddin Eripuddin   +2 more
openalex   +1 more source

Journées REPHY 2002. Nantes, 20 et 21 mars 2002. Compte-rendu des exposés [PDF]

, 2004
Cathérine Belin
openalex