Results 91 to 100 of about 140,234 (311)

Capabilities Development: From International Space Station and the Moon to Mars [PDF]

open access: yes
The President of the United States, in signing Space Policy Directive-1, directed the NASA Administrator to lead an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar ...
Boggs, Kathleen Gallagher   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Mars Oxygen ISRU Experiment (MOXIE)-Preparing for human Mars exploration. [PDF]

open access: yesSci Adv, 2022
Hoffman JA   +23 more
europepmc   +1 more source

Boron enrichment in Martian clay [PDF]

open access: yes, 2013
We have detected a concentration of boron in martian clay far in excess of that in any previously reported extra-terrestrial object. This enrichment indicates that the chemistry necessary for the formation of ribose, a key component of RNA, could have ...
Freeland, Stephen J.   +4 more
core   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Subspace Method-based Blind SNR Estimation for Communication between Orbiters in Mars Exploration

open access: yesITM Web of Conferences, 2017
In Mars exploration the effective time of communication between orbiters is short, and the relative distance and gesture between them change fast. The signal to noise ratio (SNR) estimation is required in receiver to change adaptively the data rate in ...
Sun Ze-Zhou   +2 more
doaj   +1 more source

Mars 94 Mission: Current plans and science [PDF]

open access: yes
The Soviet Space Program proposes large-scale investigations of Mars as one of the most important trends for the next 10 to 15 years. The objectives include global studies of the surface of Mars, its atmosphere, and the return of soil samples to Earth ...
Marov, Mikhail YA., Mukhin, Lev
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Trade studies for nuclear space power systems [PDF]

open access: yes
As human visions of space applications expand and as we probe further out into the universe, our needs for power will also expand, and missions will evolve which are enabled by nuclear power.
Bents, David J.   +2 more
core   +1 more source

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