Distributed Cognition and the Experience of Presence in the Mars Exploration Rover Mission. [PDF]
Chiappe D, Vervaeke J.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Acoustic monitoring of laser-induced phase transitions in minerals: implication for Mars exploration with SuperCam. [PDF]
Chide B +7 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A Mars Environment Chamber Coupled with Multiple In Situ Spectral Sensors for Mars Exploration. [PDF]
Wu Z +7 more
europepmc +1 more source
Site selection for manned Mars landings: A geological perspective [PDF]
Issues relating to the selection of initial landing sites for manned Mars missions are discussed from a geological viewpoint. The two prime objectives for initial manned exploration should be the youngest unambiguous lava flows (to tie down the late end ...
Spudis, Paul D.
core +1 more source
Benefits of Using a Mars Forward Strategy for Lunar Surface Systems [PDF]
This paper identifies potential risk reduction, cost savings and programmatic procurement benefits of a Mars Forward Lunar Surface System architecture that provides commonality or evolutionary development paths for lunar surface system elements ...
Griffin, Brand +3 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
From machine learning to transfer learning in laser-induced breakdown spectroscopy analysis of rocks for Mars exploration. [PDF]
Sun C +9 more
europepmc +1 more source
Marshall Space Flight Center Research and Technology Report 2019 [PDF]
Today, our calling to explore is greater than ever before, and here at Marshall Space Flight Centerwe make human deep space exploration possible. A key goal for Artemis is demonstrating and perfecting capabilities on the Moon for technologies needed for ...
Dankanich, John W., Morris, Heather C.
core +1 more source

