Results 111 to 120 of about 3,579 (281)

A multi-distance laser-induced breakdown spectroscopy data classification method based on deep convolutional neural network and spectral sample weight optimization. [PDF]

Sci Rep
Zhang X, Li L, Cui Z, Xu W, Xu X, Shu R, Liu X, Wang J.   +7 more
europepmc   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

Advanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau, Monica A. Rionda, Evelyn Cho, Jamison G. Clark, Robin E. Kruger, Ruth K. Chan‐Sui, Vasantha Padmanabhan, Molly B. Moravek, Ariella Shikanov   +8 more
wiley   +1 more source

Bow shock oscillations of Mars under weakly disturbed solar wind conditions. [PDF]

Nat Commun
Cheng L, Wang Y, Ma Y, Lillis R, Halekas J, Langlais B, Zhang T, Zhang A, Wang G, Xiao S, Zou Z, Chi Y, Hao X, Li Y, Pan Z, Liu K.   +15 more
europepmc   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Liquid water might not be the only answer: Evaluating pore-filling materials in the Martian crust. [PDF]

Proc Natl Acad Sci U S A
Xiao W, Pan L, Wang Y, Li J.
europepmc   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Detection of visible-wavelength aurora on Mars. [PDF]

Sci Adv
Knutsen EW, McConnochie TH, Lemmon M, Donaldson C, Francis R, Legett C, Viet SB, Soret L, Toledo D, Apéstigue V, Witasse O, Montmessin F, Jolitz R, Schneider NM, Tamppari L, Cousin A, Wiens RC, Maurice S, Bell JF, Forni O, Lasue J, Pilleri P, Bertrand T, Patel P, Schröder S, Curry S, Lee CO, Rahmati A.   +27 more
europepmc   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Reply to Xiao et al.: A wet or dry Martian mid-crust, that is only part of the question. [PDF]

Proc Natl Acad Sci U S A
Wright V, Morzfeld M, Manga M.
europepmc   +1 more source

Enhancing Fatigue Performance by Tuning of Residual Stresses in Welded Joints through Nanometallic Multilayer

Advanced Engineering Materials, EarlyView.
This study investigates the fundamental mechanisms of a novel postweld treatment that significantly enhances fatigue performance through engineered residual stress (RS) states. A multiscale approach correlates tensile RS in the nanometallic multilayer coating with corresponding compressive RS in the steel substrate, thereby reducing localized stress ...
Niclas Spalek, Guilherme Abreu Faria, Anton Davydok, Marcus Rutner   +3 more
wiley   +1 more source