Results 51 to 60 of about 13,637 (293)

The martyr-figure in French theatre,1596-1675 [PDF]

open access: yes, 2001
This doctoral project is the first comprehensive study of plays about Christian martyrdom on the French stage from 1596 to 1675.1 have compiled a corpus of such tragedies (Appendix).
Scott, Paul Adam
core  

Simultaneous replacement of the aortic valve and hip joint in a patient with critical aortic stenosis and femoral neck fracture

open access: yesВестник хирургии имени И.И. Грекова
Concomitant cardiovascular diseases in elderly patients with a hip fracture significantly increase the risk of developing postoperative complications.
S. V. Petrov   +6 more
doaj   +1 more source

Narrative Function (Semiotic square) in the paintings of Prayer, Majnun, Blood Contract, and Hazrat Ali Akbar by Khashayar Qazizadeh [PDF]

open access: yesReligion & Communication, 2015
In the discourse analysis of Khashayar Qazizadeh's paintings, it has been tried to pass through single signs, macro-signs, micro-signs, or a combination of signs so that we can go beyond signs, i.e.
Ali Abbasi
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Morality Martyr Homology

open access: yes, 2023
This article explicates a morality martyr homology with three characteristics: amoral actions against good characters, introspection, and a fatalistic final act.
Perks, Lisa
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

(W)riting and (de)scribing martyrdom: The church’s construction of Manche Masemola

open access: yesHTS Teologiese Studies/Theological Studies, 2020
The purpose of this article is to describe how the Manche Masemola narrative crafts and constructs her as a martyr; dying in defence of her faith in the face of fierce religious competition between her Sepedi culture and Anglican faith.
Sekgothe Mokgoatšana
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Métamorphoses théâtrales de l’hagiographie : usages esthétique et politique de la fictionnalisation des légendes

open access: yesLes Dossiers du GRIHL, 2015
This study deals with the dramatisation of hagiographical legends in France, in the seventeenth century. We would like to shed light on the theatrical uses of the saint character, focusing on the way dramatists insert fiction into the legends.
Anne Teulade
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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