Results 11 to 20 of about 7,464 (216)
Contrasting effects of filamin A and B proteins in modulating filovirus entry.
PLoS Pathogens, 2023 Ebola (EBOV) and Marburg viruses (MARV) cause severe hemorrhagic fever associated with high mortality rates in humans. A better understanding of filovirus-host interactions that regulate the EBOV and MARV lifecycles can provide biological and mechanistic
Ariel Shepley-McTaggart +7 more
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Viruses, 2018 Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
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Protection Against Marburg Virus Using a Recombinant VSV-Vaccine Depends on T and B Cell Activation
Frontiers in Immunology, 2019 Marburg virus (MARV) is the causative agent of hemorrhagic fever outbreaks with high case fatality rates. Closely related to Ebola virus, MARV is a filamentous virus with a negative-sense, single-stranded RNA genome.
Andrea Marzi +8 more
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Vaccines, 2022 Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development.
Kendra J. Alfson +17 more
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Marburgvirus Hijacks Nrf2-Dependent Pathway by Targeting Nrf2-Negative Regulator Keap1
Cell Reports, 2014 Marburg virus (MARV) has a high fatality rate in humans, causing hemorrhagic fever characterized by massive viral replication and dysregulated inflammation.
Audrey Page +14 more
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Preparation of Class Y Immunoglobulins that Neutralize the Marburg Virus
Проблемы особо опасных инфекций, 2021 The aim was to study the possibility of inducing Marburg-neutralizing chicken antibodies (MARV) using various immunogens.Materials and methods. Recombinant vaccinia virus expressing the surface glycoprotein (GP) transgene MARV of Musoke strain and ...
O. A. Polezhaeva +7 more
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Detailed data on MARV-positive Rousettus aegyptiacus.
, 2023 Detailed data on MARV-positive Rousettus aegyptiacus.
Ivan S. Kholodilov (15361345) +16 more
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Emerging Microbes and Infections, 2023 Infection with Marburg virus (MARV), the causative agent of Marburg virus disease (MVD), results in haemorrhagic disease and high case fatality rates (>40%) in humans. Despite its public health relevance, there are no licensed vaccines or therapeutics to
Cecilia A. Prator +8 more
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Marburg virus evades interferon responses by a mechanism distinct from ebola virus.
PLoS Pathogens, 2010 Previous studies have demonstrated that Marburg viruses (MARV) and Ebola viruses (EBOV) inhibit interferon (IFN)-alpha/beta signaling but utilize different mechanisms. EBOV inhibits IFN signaling via its VP24 protein which blocks the nuclear accumulation
Charalampos Valmas +8 more
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