Results 91 to 100 of about 54,464 (316)
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
“Note on sex for the aged widower”: On André Brink’s The Rights of Desire
Tydskrif vir Letterkunde, 2018 This article examines the representation of masculinity in André Brink’s novel, The Rights of Desire. Following a remark in Roger Boylan’s review of the novel in the Boston Review; this analysis concentrates on Brink’s depiction of Afrikaner masculinity ...
Marius Crous
doaj
Measuring Restrictive Masculinity: Development and Implementation Within University Students
Social SciencesRestrictive masculinity is a rigid construct of how to define manliness that is associated with several health harms. The current study sought to develop a brief questionnaire to measure restrictive masculinity.
Jonathan K. Noel +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Seeking a new normality : masculinity, interaction and a gluten free diet
, 2016 Ethel Kautto +5 more
openalex +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Image of Incriminated Masculinity in Crime Narratives - A Hegemonic Approach
Horyzonty WychowaniaRESEARCH OBJECTIVE: The aim of this article is to characterize the portrayal of incriminated masculinity in crime narratives. THE RESEARCH PROBLEM AND METHODS: Three narrative tendencies creating the image of masculinity were identified through a ...
Olga Pankalla
doaj +1 more source