Results 81 to 90 of about 360,067 (302)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Urban Low-Income African American Men, HIV/AIDS, and Gender Identity [PDF]

open access: yes, 1997
This article explores the sociocultural meanings attached to sexual behaviors and conceptions of masculinity among low-income African-American males.
Tony L. Whitehead
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Re-Thinking Aspiration and Hegemonic Masculinity in Transnational Context

open access: yesMasculinities and Social Change, 2014
This article offers a contribution to the on-going critical analysis of the concept hegemonic masculinity. However, not in a way that seeks the demise or supersession of the concept but rather to offer a theoretical development that brings into focus ...
Richard Howson
doaj   +1 more source

Erectile dysfunction, masculinity, and psychosocial outcomes: a review of the experiences of men after prostate cancer treatment

open access: yesTranslational Andrology and Urology, 2017
Prostate cancer (PC) treatment side-effects such as erectile dysfunction (ED) can impact men’s quality of life (QoL), psychosocial and psycho-sexual adjustment.
S. Chambers   +3 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Energy impoverishment and burns: The case for an expedited, safe and inclusive energy transition in South Africa

open access: yesSouth African Journal of Science, 2022
Ashley van Niekerk   +3 more
doaj   +1 more source

Mitos Maskulinitas Pada Tokoh Utama (Analisis Semiotika Roland Barthes Dalam Film Jakarta Vs Everybody) [PDF]

open access: yes
Using Roland Barthes' semiotic techniques, this research focuses on examining the myth of masculinity in the 2020 film "Jakarta Vs Everybody". By using the critical paradigm and Barthes' semiotic theory to determine denotation, connotation and myth, the ...
Juliantoro, M. Daffa Akbar
core  

"The land of my dreams": the gendered utopian dreams and disenchantment of British literary ex-combatants of the Great War [PDF]

open access: yes, 2011
The last two decades have seen a slow shift in the academic understanding of the impact of the Great War on concepts of gender in interwar Britain. The work of a small group of cultural historians, following in the footsteps of Rosa Maria Bracco, has ...
Cullen, Stephen Michael
core   +1 more source

Masculinity and affect: new possibilities, new agendas

open access: yesNorma, 2018
The aim of this special issue is to create a greater dialogue between affect studies and masculinity studies. The contributions to the issue explore how affect functions as non-discursive intensities that may enable new forms of gendered subjectivities ...
Todd W. Reeser, Lucas Gottzén
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy