Results 71 to 80 of about 20,186 (266)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Representations of Toxic Masculinity on Nate Jacobs in Euphoria (2019)
SALEEDespite some changes in how masculinity is portrayed over time, certain disturbing patterns and characteristics continue. Yet, popular media exposure may be the primary way that children and most adults learn about others as well as absorb and ...
Annisa Ayuretno, Putri Rindu Kinasih
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The representation of Arab masculinity in advertising
الباحث الإعلاميThe aim of this study is to utilize Semiotic analysis to analyze the representation of Gulf men in advertising a Kuwaiti brand. Based on two YouTube commercials as a case study, this article asks, How is Arab masculinity represented in advertising?
Abdullah Kassem Abdullah, Noha Mellor
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Tough, sensitive and sincere: how adolescent boys manage masculinities and emotions
International Journal of Adolescence and Youth, 2016 This study aimed to explore adolescent boys’ views of masculinity and emotion management and their potential effects on well-being. Interviews with 33 adolescent boys aged 16–17 years in Sweden were analysed using grounded theory.
Eva Randell +4 more
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Die Darstelung der Männlichkeit im Roman "Verführungen" (1996) von Marlene Streeruwitz
Brünner Beiträge zur Germanistik und Nordistik, 2014 The paper deals with an interpretation of the masculinity in the novel Verführungen, written by Marlene Streeruwitz (∗1950), an Austrian author with a strong feminist position. The hegemonic masculinity represents the most dominant form of masculinity in
Dagmar Vincze
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source