Results 81 to 90 of about 54,464 (316)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Die Darstelung der Männlichkeit im Roman "Verführungen" (1996) von Marlene Streeruwitz

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2014
The paper deals with an interpretation of the masculinity in the novel Verführungen, written by Marlene Streeruwitz (∗1950), an Austrian author with a strong feminist position. The hegemonic masculinity represents the most dominant form of masculinity in
Dagmar Vincze
doaj  

Coğrafyaya Erkeklik Kavramının Yerleşmesi ve Hegemonik Erkekliğe Yaklaşımlar

open access: yesCoğrafi Bilimler Dergisi
This study explains the establishment of the concept of masculinity in the discipline of geography and how hegemonic masculinity is formed in places and places.
Miyase Yalçın
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The Representations of Toxic Masculinity on Nate Jacobs in Euphoria (2019)

open access: yesSALEE
Despite some changes in how masculinity is portrayed over time, certain disturbing patterns and characteristics continue. Yet, popular media exposure may be the primary way that children and most adults learn about others as well as absorb and ...
Annisa Ayuretno, Putri Rindu Kinasih
doaj   +1 more source

Tough, sensitive and sincere: how adolescent boys manage masculinities and emotions

open access: yesInternational Journal of Adolescence and Youth, 2016
This study aimed to explore adolescent boys’ views of masculinity and emotion management and their potential effects on well-being. Interviews with 33 adolescent boys aged 16–17 years in Sweden were analysed using grounded theory.
Eva Randell   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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