Results 61 to 70 of about 646,914 (294)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Effect of face mask on pulmonary artery pressure during echocardiography in children and adolescents [PDF]

open access: yesClinical and Experimental Pediatrics
Background Face masks have become an important tool for preventing the spread of respiratory diseases. However, we hypothesized that face masks with reduced nasal airflow may alter pulmonary artery systolic pressure (PASP).
Alireza Ahmadi   +2 more
doaj   +1 more source

Surgical mask use by healthcare personnel to prevent COVID‐19 spread in a long‐term care facility

open access: yesJournal of General and Family Medicine, 2021
Long‐term care facilities are a recognized high‐risk setting for severe outcomes during the coronavirus disease 2019 (COVID‐19) outbreak. This study describes a COVID‐19 outbreak in a long‐term care facility in Japan.
Toshikazu Abe   +6 more
doaj   +1 more source

Anti-SARS-CoV-2 Activity of Surgical Masks Infused with Quaternary Ammonium Salts

open access: yesViruses, 2021
The SARS-CoV-2 pandemic has highlighted the need for protective and effective personal protective equipment (PPE). Research has shown that SARS-CoV-2 can survive on personal protective equipment, such as commonly used surgical masks.
Gary S. Selwyn   +2 more
doaj   +1 more source

The Great Observatories Origins Deep Survey - VLT/VIMOS Spectroscopy in the GOODS-South Field: Part II

open access: yes, 2010
We present the full data set of the VIMOS spectroscopic campaign of the ESO/GOODS program in the CDFS, which complements the FORS2 ESO/GOODS spectroscopic campaign.
A. Rettura   +47 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Analysis and Optimization of Aperture Design in Computational Imaging

open access: yes, 2017
There is growing interest in the use of coded aperture imaging systems for a variety of applications. Using an analysis framework based on mutual information, we examine the fundamental limits of such systems---and the associated optimum aperture coding--
Thrampoulidis, Christos   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Rectangular-Mask Coronagraphs for High-Contrast Imaging

open access: yes, 2004
We present yet another new family of masks for high-contrast imaging as required for the to-be-built terrestrial planet finder space telescope. The ``best'' design involves a square entrance pupil having a 4-vane spider, a square image-plane mask ...
Kasdin, N. Jeremy   +2 more
core   +1 more source

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