Results 11 to 20 of about 17,128 (260)
Revista de la Sociedad Argentina de DiabetesEl hígado graso, tambien conocido comoesteatosis hépatica. Es una condición en la que se acumula grasa en lascélulas del hígado. En muchas personas no presenta síntomas de inicio,pero si no se detecta y controla, puede avanzar y causar dañohépatico.
Ballesteros Silva, Karla Liliana +5 more
openaire +2 more sources
MASLD treatment—a shift in the paradigm is imminent
Frontiers in Medicine, 2023 MASLD prevalence is growing towards the leading cause of end-stage liver disease. Up to today, the most effective treatment is weight loss. Weight loss interventions are moving from lifestyle changes to bariatric surgery or endoscopy, and, more recently, to a new wave of anti-obesity drugs that can compete with bariatric surgery. Liver-targeted therapy
Mariana Verdelho Machado +1 more
openaire +4 more sources
BiomoleculesMetabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most common liver disease worldwide in recent years. MASLD commonly presents as simple hepatic steatosis, but ~25% of patients develop liver inflammation, progressive fibrosis, liver cirrhosis and related hepatocellular carcinoma.
Moritz Meyer +3 more
openaire +3 more sources
BMB ReportsMetabolic Dysfunction Associated Steatotic Liver Disease (MASLD) and its progressive form, Metabolic Dysfunction Associated Steatohepatitis (MASH), represent significant health concerns associated with the metabolic syndrome. These conditions are characterized by excessive hepatic fat accumulation, inflammation, and potential progression to cirrhosis ...
Sanjeeb Shrestha +2 more
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
The role of tryptophan hydroxylase-1 in metabolic dysfunction-associated steatotic liver disease. [PDF]
Pediatr InvestigSilencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Jia S, Ye X, Wang Z, Wu J.
europepmc +2 more sources
JAMA Internal MedicineThis Clinical Insights discusses new diagnostic criteria, risk stratification, and emerging treatments of metabolic dysfunction–associated steatotic liver disease (MASLD; formerly nonalcoholic fatty liver disease).
Zhang, G. Y., Brandman, D.
openaire +3 more sources
Arthritis Care &Research, Accepted Article.Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang +4 more
wiley +1 more source
Indian Journal of Endocrinology and MetabolismIntroduction: Liver fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly related to hepatic and extrahepatic outcomes.
Rajat Deb +7 more
doaj +1 more source