Results 51 to 60 of about 17,128 (260)

Transferrin combined with alanine aminotransferase and body mass index improves non-invasive diagnosis of metabolic dysfunction-associated steatohepatitis

Endocrine Connections
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease globally, with over 20% of patients progressing to metabolic dysfunction-associated steatohepatitis (MASH), which carries a high risk
Xinyi Wang, He He, Libo Liang
doaj   +1 more source

Machine Learning–Based Comparative Analysis of Blood Cell–Derived Inflammatory Indices for Predicting MAFLD and Liver Fibrosis: Evidence From NHANES 2017–2020

Journal of Clinical Laboratory Analysis, EarlyView.
This research assesses the correlations and diagnostic efficacy of blood cell‐derived inflammatory indicators in predicting metabolic dysfunction‐associated fatty liver disease (MAFLD) and liver fibrosis using NHANES 2017–2020 data. AISI had the highest predictive capability for MAFLD, while PLR served as the most efficacious indicator for fibrosis ...
Hao Chen, Qinmei Chen, Xiangqian Wang, Yixian He, Xiqiao Zhou   +4 more
wiley   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

Journal of Clinical Ultrasound, EarlyView.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio, Maria Angelica Jungles Malikoski, Eduardo Henrique Bonotto, Sandra Monica Tochetto, Marco Stephan Lofrano‐Alves   +4 more
wiley   +1 more source

Inflammation in MASLD progression and cancer

JHEP Reports
Steatotic liver diseases include metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-associated liver disease, and metabolic dysfunction and alcohol-related liver disease (MetALD), encompassing a spectrum of metabolic liver disorders that range from steatosis to steatohepatitis, cirrhosis, and hepatocellular carcinoma.
Yeonsoo Kim, Yunseo Park, Hyunsoo Rho, Tiantian Yao, Bin Gao, Seonghwan Hwang   +5 more
openaire   +2 more sources

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Potential pharmacotherapy pathways in metabolic dysfunction-associated steatotic liver disease

Clinical & Experimental Hepatology
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide, one of the leading causes of cirrhosis, hepatocellular carcinoma and liver transplantation in developed countries, and an important ...
Paweł Rajewski, Jakub Cieściński, Piotr Rajewski, Szymon Suwała, Alicja Rajewska, Maciej Potasz   +5 more
doaj   +1 more source

High‐Throughput Quantitative Chemical Shift‐Encoded MRI of the Liver

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Access to MRI is limited by lengthy exam times and inefficient utilization. Focused protocols can reduce exam times, but workflow variability and inefficient room turnaround contribute to conservative scheduling with long exam slots.
Garrett C. Fullerton, Jiayi Tang, Jitka Starekova, Julius F. Heidenreich, Ali Pirasteh, David T. Harris, Daiki Tamada, Collin J. Buelo, Dan W. Rettmann, Diego Hernando, Scott B. Reeder   +10 more
wiley   +1 more source

The Hepatoprotective Potential of Alpha-Lipoic Acid Mechanisms and Translational Evidence

Baghdad Journal of Biochemistry and Applied Biological Sciences
Background: Liver diseases remain a major global health challenge with limited effective therapies. Alpha-lipoic acid (ALA), a mitochondrial cofactor, has gained attention for its antioxidant and anti inflammatory properties.
Huda Ayad Al-Mosawi, Ausama Ayob Jaccob, Muhsin S.G. Al-Mozie'l   +2 more
doaj   +1 more source

Probiotics and intestinal permeability in adults with metabolic dysfunction‐associated steatohepatitis: A secondary analysis of a randomized clinical trial

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva‐Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe‐Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba   +10 more
wiley   +1 more source

Hypertransaminasemia in hospitalized children: Insights from a national multicenter study by the Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Hypertransaminasemia is a frequent finding in hospitalized children with common pediatric illnesses, often considered a transitory phenomenon associated with systemic inflammation/injury. This study aims to assess the prevalence and causes of incidentally detected hypertransaminasemia in children admitted to general pediatric units ...
Angelo Di Giorgio, Giusy Ranucci, Pietro Aliberti, Carmela Pia Senatore, Camilla Calì, Angelo Mazza, Francesca Sbravati, Patrizia Alvisi, Maurizio Giuseppe Fuoti, Ilaria Rochira, Antonio Marseglia, Maria Rosa Pastore, Annalisa Madeo, Alessandro La Rosa, Federica Ferrari, Fortunata Sabrina Civitelli, Valentina Maffini, Icilio Dodi, Serena della Femina, Andrea Colangelo, Lorenzo D'Antiga, Claudia Mandato   +21 more
wiley   +1 more source