Results 91 to 100 of about 3,618,957 (252)
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
How to Remove Barriers to Entry – From Mass Appraisal to Fee Appraisal Accreditation
Industry partners and leading experts have come together to form IAAO’s Mass Appraisal Experience Credit Task Force. Attendees will leave the session empowered with the understanding and knowledge of the available tools to help advocate for acceptance of
Hayes, Kevin, CAE, RES, CFE +2 more
core
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Uporaba načina kapitalizacije donosa v sistemu množičnega vrednotenja posebnih nepremičnin / Application of the income approach in the special real properties mass appraisal system [PDF]
SI: Prispevek obravnava uporabo načina kapitalizacije donosa v slovenskem sistemu množičnega vrednotenja nepremičnin pri modelih posebnih nepremičnin, to je nepremičnin za proizvodnjo električne energije, nepremičnin za izkoriščanje mineralnih ...
Marko Suhadolc
doaj
Mass Appraisal is a TEAM Sport
Mass appraisal is the systematic creation, application, and testing of values by a group of people. In simple terms, it is a TEAM sport. This session will explore the hallmarks of a healthy team, a healthy culture, and the proven benefits of ...
Niederklein, Derrick D, AAS
core
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source

