Results 81 to 90 of about 5,413,419 (288)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Efficiency of Nitrogen and Flue Gas as Operating Gases in Explosive Decompression Pretreatment

open access: yesEnergies, 2018
As the pretreatment process is the most expensive and energy-consuming step in the overall second generation bioethanol production process, it is vital that it is studied and optimized in order to be able to develop the most efficient production process.
Merlin Raud, Vahur Rooni, Timo Kikas
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Influence of canopy development in the vineyard on spray deposition from a tunnel sprayer

open access: yesJournal of Agricultural Engineering, 2018
Spray deposition from a tunnel, air-assisted sprayer was analysed during the whole season, following canopy development in a vertical-shoot-positioned vineyard.
Gianfranco Pergher, Nicola Zucchiatti
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Surface mass balance along the K-transect in West Greenland

open access: yes, 2012
A 21-year record is presented of surface mass balance measurements along the K-transect. The series covers the period 1990-2011. Data are available at 8 sites along a transect over an altitude range of 390 - 1850 m at approximately 67° N in West ...
Snellen, Henk   +11 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Point measurements of annual mass balance of Freya Glacier, Greenland, in 2014/2015

open access: yes, 2017
Point measurements of annual mass balance of Freya Glacier, Greenland, in 2014 ...
Citterio, Michele   +7 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Mass balance on elevation zones of Freya Glacier, Greenland, in 2015/2016

open access: yes, 2018
Mass balance on elevation zones of Freya Glacier, Greenland, in 2015 ...
Citterio, Michele   +5 more
core   +1 more source

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