Results 161 to 170 of about 26,667,629 (348)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

GALSBI-SPS: A stellar population synthesis-based galaxy population model for cosmology and galaxy evolution applications

open access: yesAstronomy & Astrophysics
Context. Next-generation photometric and spectroscopic galaxy surveys will enable unprecedented tests of the concordance cosmological model and of galaxy formation and evolution.
Tortorelli Luca   +6 more
doaj   +1 more source

Function of Neologisms in Electronic Mass Media Headlines

open access: yesНаучный диалог, 2019
The features of the usage of word-formative neologisms in the aspect of the implementation of the functions of media text headline (on the material of titles of electronic media texts) are considered.
V. A. Toropkina
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

GLIMPSE-D: Metallicity decline in faint galaxies: Implications for [O III]+Hβ luminosity function and re-ionisation budget

open access: yesAstronomy & Astrophysics
We report the measurement of the R3 = [O III] λ5008/Hβ ratios for 54 galaxies in the GLIMPSE-D survey. Thanks to gravitational lensing, our sample includes galaxies with −20 ≲ MUV 
Korber Damien   +15 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The mass functions of multiple stellar populations in 47 Tucanae

open access: yesAstronomy & Astrophysics
We used a combination of James Webb Space Telescope (JWST) and Hubble Space Telescope (HST) observations to investigate the mass functions (MFs) of the different stellar populations in the globular cluster (GC) 47 Tucanae (NGC 104) over a wide stellar ...
Scalco M.   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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