Results 181 to 190 of about 26,667,629 (348)

The Tail of the HI Mass Function

, 2000
8 pages, presented at Mapping the Hidden Universe: The Universe in HI.
Schneider, SE, Rosenberg, JL
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Generalization of Dempster–Shafer theory: A complex mass function

Applied intelligence (Boston), 2020
Fuyuan Xiao
semanticscholar   +1 more source

Probing the Composition, Assembly and Activity of Protein Molecular Machines using Native Mass Spectrometry [PDF]

, 2017
Native mass spectrometry and mass spectrometry in general, are powerful analytical tools for studying proteins and protein complexes. Native mass spectrometry may provide accurate mass measurements of large macromolecular assemblies enabling the ...
van de Waterbeemd, M.J., Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Mitochondrial damage drives T-cell immunometabolic paralysis after major surgery

EMBO Molecular Medicine
Cytotoxic T cell (CTL) dysfunction is a hallmark of immune paralysis after major surgery, increasing susceptibility to severe nosocomial infections and contributing to mortality in critically ill patients. The mechanisms remain poorly understood.
Simon Hirschberger, Martin B Müller, Hannah Mascolo, Melissa Seitz, Stefan Nibler, David Effinger, Kun Lu, Joscha Büch, Martin Bender, Tobias Kammerer, Sven Peterß, Karin Kleigrewe, Miriam Abele, Teresa Barth, Olga Kushnir, Axel Imhof, Steffen Dietzel, Bernd Wegener, Ralf Sowa, Frank Vogel, Peter Lamm, Roland Tomasi, Kristian Unger, Markus Sperandio, Erich Kilger, Simone Kreth, Max Hübner   +26 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A conditional probability mass function

, 2013
The probability mass function of a pair of discrete random variables (X,Y) is the function f(x,y)=P(X=x,Y=y). The conditional mass function of Y given X is the function f(y|x)=P(Y=y|X=x).
Boucher, Chris
core   +3 more sources

Halo Mass Function

, 2005
6 pages, Latex, 4 figures, to be published in ``IMF@50: A Fest-Colloquium in honor of Edwin E. Salpeter,'' held at Abbazia di Spineto, Siena, Italy, May 16-20, 2004. Kluwer Academic Publishers; edited by E. Corbelli, F.
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source