Results 51 to 60 of about 1,918,733 (356)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effect of Spruce Wood Density on Selected Fire-Technical Parameters during Thermal Loading

open access: yesApplied Sciences, 2023
The paper evaluates the effect of spruce wood density on the parameters of mass loss and mass loss rate during exposure to thermal load. The intention was to determine whether the effect of density is still evident after the application of flame ...
Patrik Mitrenga   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The synergistic effects of a leaf mixture on decomposition change with a period of terrestrial exposure prior to immersion in a stream

open access: yesEcology and Evolution
The effect of mixing litter on decomposition has received considerable attention in terrestrial and aquatic (but rarely in both) ecosystems, with a striking lack of consensus in the obtained results.
Manuela Abelho, Enrique Descals
doaj   +1 more source

Eddington and Mass Loss [PDF]

open access: yesHighlights of Astronomy, 1983
AbstractThis joint discussion is dedicated to the memory of Sir Arthur Eddington who was born 100 years ago. He laid the foundation of much work on stellar evolution, which was summed up in his book The Internal Constitution of the Stars (ICS) which appeared in 1926.
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessing the natural durability of different tropical timbers in soil-bed tests

open access: yesMaderas: Ciencia y Tecnología, 2019
Ground contact speeds up timber decay because of the large number of microorganisms in soil. This study, we assessed the natural durability of seven tropical species using the European standard EN 807 (2001). We embedded samples of Dalbergia granadillo,
Serafín Colín-Urieta   +5 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Preliminary estimates of mass-loss rates, changes in stable isotope composition, and invertebrate colonisation of evergreen and deciduous leaves in a Waikato, New Zealand, stream.

open access: yes, 1999
Rates of mass loss are important in the choice of tree species used in riparian rehabilitation because leaves that break down fast should contribute to stream food-webs more rapidly than leaves that break down more slowly.
Laboyrie, J. Lee   +3 more
core   +1 more source

Radio observations of stellar mass loss [PDF]

open access: yesSymposium - International Astronomical Union, 1979
A program to search for steady-state thermal emissions from stars has been in progress for several years in Canada (Purton 1976). In this program we have specifically excluded flaring objects (such as β Lyr or HR1099) where non-thermal emission is probably responsible.
Sun Kwok, C. R. Purton
openaire   +1 more source

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