Results 61 to 70 of about 1,918,733 (356)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The impact of mass-loss on the evolution and pre-supernova properties of red supergiants [PDF]

open access: yes, 2014
The post main-sequence evolution of massive stars is very sensitive to many parameters of the stellar models. Key parameters are the mixing processes, the metallicity, the mass-loss rate and the effect of a close companion.

core  

On the Consequences of Mass Loss from Intermediate-Mass Stars [PDF]

open access: yesInternational Astronomical Union Colloquium, 1981
There are two major effects of mass loss from stars of intermediate mass. First, the ultimate fate of such stars--whether they become supernovae of the type that leave no condensed remnant or whether they become white dwarfs--is extremely sensitive to the rate at which they lose mass during the last portion of their nuclear-burning lives.
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identification of oil palm (elaeis guineensis) spear leaf metabolites using mass spectrometry and neutral loss analysis. [PDF]

open access: yes, 2013
Plant metabolites characterisation is an arduous challenge due to their structural diversity as a result of complicated biosynthetic pathways. These metabolites are not only important for metabolic events description but are also harnessed as valuable ...
Abas, Faridah   +5 more
core  

Mass Transfer in Mira-Type Binaries

open access: yesOpen Astronomy, 2012
Detached, symbiotic binaries are generally assumed to interact via Bondi-Hoyle-Littleton (BHL) wind accretion. However, the accretion rates and outflow geometries that result from this mass-transfer mechanism cannot adequately explain the observations of
Mohamed S., Podsiadlowski Ph.
doaj   +1 more source

EARLY STAGES OF NEEDLE LITTER DECOMPOSITION IN A COWBERRY PINE STAND IN THE MIDDLE TAIGA OF KARELIA

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2019
Plant litter decomposes via several stages, the most intensive one being the early stage, when it is mostly readily extractable compounds that are released, contributing to annualnutrient cycling. The aim of this study was to find patterns in the rate of
Anton Solodovnikov
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Critical Rates of Stellar Mass Loss [PDF]

open access: yesSymposium - International Astronomical Union, 1979
Many of the effects of mass loss on OB stars have now been explored. Mass loss will cause a star to be overluminous for its mass (though less luminous than a star of its original mass) and, for moderate mass-loss rates, the luminosity decreases at the same rate as the mass contained in the convective core decreases causing the main sequence lifetime to
D. S. P. Dearborn, J. B. Blake
openaire   +1 more source

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