Results 71 to 80 of about 4,507,065 (293)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Highlights of Astronomy, 1983 AbstractThis joint discussion is dedicated to the memory of Sir Arthur Eddington who was born 100 years ago. He laid the foundation of much work on stellar evolution, which was summed up in his book The Internal Constitution of the Stars (ICS) which appeared in 1926.
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Forestist, 2008 Serpııla lacıyınans (YVulfeıı:Fr.) S clıroeter, the d ry ro t fungus, is generally accepted as oııe of tlıe m ost ecoııom ically iıııp o rtan t w ood deg rad in g fungi in som e te m p erate regions of the vvorld.
Coşkun Köse
doaj +1 more source
Pore pressure evolution and mass loss of broken gangue during the seepage [PDF]
Royal Society Open Science, 2018 Broken gangue consists of different particles, and it has more complicated seepage characteristics than intact rock sample. Using the self-designed instrument, the permeability, mass loss and pore pressure of crushed gangue during the seepage are tested.
Jixiong Zhang +3 more
doaj +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Acta Agronómica, 2018 La producción de frutilla en Paraguay es realizada por pequeños productores, usando escasa tecnología y obtención de baja productividad, con la necesidad de ampliar los genotipos y la tecnología utilizada. El objetivo de esta investigación fue evaluar la
Victoria Rossmary Santacruz-Oviedo +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source