Results 81 to 90 of about 3,116,970 (291)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Chasing Success: A Cultivated Reality [PDF]

, 2018
George Gerbner’s cultivation theory claims that people who consume heavy amounts of media are more likely to be influenced by those messages to believe the media reality as opposed to actual reality.
Bevillard, Anastasia
core   +1 more source

How the mass media report social statistics: A case study concerning research on end-of-life decisions [PDF]

, 2010
This is the post-print version of the final paper published in Social Science & Medicine. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Bauman, Bell, Best, Best, Best, Boyce, Cicourel, Clive Seale, Deacon, Entwistle, Fenton, Fenton, Galtung, Gorer, Harcup, Hausmann, Jackson, Kitzinger, Kitzinger, Kuhse, Langer, Lewis, McInerney, McInerney, McInerney, Mellor, Nelkin, Osborne, Pollock, Rietjens, Schmierbach, Seale, Seale, Seale, Seale, Seale, Seale, Seale, Signorielli, Sparks, Sykes, van der Heide, van der Maas, Wakefield, Williams   +44 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Greek Young Audience Perceptions and Beliefs on Different Aspects of TV Watching

Journalism and Media
Television plays a significant role in shaping the beliefs, perceptions, and attitudes of young individuals. Understanding the factors that influence these beliefs is essential for comprehending the impact of television programming on the youth ...
Anna G. Orfanidou, Nikos S. Panagiotou
doaj   +1 more source

Branded Media Text as Communicative-integration Model of Interaction with Audience

SHS Web of Conferences, 2018
The development dynamics of information and communication technologies (ICTs), especially network providing expansion of interpersonal and mass communications, radically changes the existing practice of distribution and representation of a media product.
Urazova Svetlana, Volkova Irina, Baranova Ekaterina, Druzhinin Andrey, Ulyura Anastasia   +4 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Exploring Greek Students’ Attitudes Toward Artificial Intelligence: Relationships with AI Ethics, Media, and Digital Literacy

Societies
This exploratory study (N = 310) investigates the relationship between students’ attitudes toward artificial intelligence (AI), their attitudes toward AI ethics, and their media and digital literacy levels.
Asimina Saklaki, Antonis Gardikiotis
doaj   +1 more source

Who is leading the campaign charts? Comparing individual popularity on old and new media [PDF]

, 2015
Traditionally, election campaigns are covered in the mass media with a strong focus on a limited number of top candidates. The question of this paper is whether this knowledge still holds today, when social media outlets are ...
D'heer, Evelien, Harder, Raymond, Van Aelst, Peter, Van Erkel, Patick   +3 more
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