Results 31 to 40 of about 194,877 (206)

Study on the Influence of Different Structure Cranks on the Dynamic Balancing of Crank-group Driving Mechanism

Jixie chuandong, 2017
In order to study the influence of different structural forms of counterweight crank on the dynamic balance of crank-group mechanism,the dynamic balance conditions is proposed based on the mass moment substitution method and moment of momentum ...
Lu Wuhui, Cao Jujiang, Wu Yao, Liu Yansong   +3 more
doaj  

Horizon Tunneling Revisited: The Case of Higher Dimensional Black Holes

, 2017
We study the tunneling of massless scalars across black hole horizons in any number of spacetime dimensions greater than three. Our analysis finds that corrections due to backreaction and the inverse dimensional expansion are naturally concomitant, and ...
Raman, Madhusudhan
core   +1 more source

Quantum Statistical Model of Nuclear Multifragmentation in the Canonical Ensemble Method [PDF]

, 1999
A quantum statistical model of nuclear multifragmentation is proposed. The recurrence equation method used within the canonical ensemble makes the model solvable and transparent to physical assumptions and allows to get results without involving the ...
A.S. Parvan, Abramowitz, Aichelin, Bauer, Bauer, Bauer, Bondorf, Bondorf, Bondorf, Botet, Bożek, Campi, Chase, Chase, Chase, Chow, Cole, Feldmeier, Friedman, Goldhaber, Gorenstein, Gross, Gulminelli, Gupta, Hahn, Hanbury-Brown, Hauger, Huang, Hubele, Kiderlen, Konopka, Landau, Le Fevre, Li, M. Płoszajczak, Majumder, Marmier, Mekjian, Müller, Ogilvie, Ohnishi, Parvan, Pochodzalla, Pratt, Pratt, Raduta, Randrup, Riordan, Rischke, Saeeduddin, Shanenko, Subramanian, Tripathy, V.D. Toneev, Zimanyi   +54 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Investigation of Dynamics of Self-Similarly Evolving Magnetic Clouds [PDF]

, 2010
Magnetic clouds (MCs) are "magnetized plasma clouds" moving in the solar wind. MCs transport magnetic flux and helicity away from the Sun. These structures are not stationary but feature temporal evolution.
A. Rogava, Berdichevsky, Bothmer, Burlaga, Burlaga, Chandrasekhar, Demoulin, Demoulin, Farrugia, Farrugia, Finn, G. Dalakishvili, G. Lapenta, Klein, Kumar, Lepping, Low, Lundquist, Nakwacki, Osherovich, Osherovich, Romashets, S. Poedts, Shapakidze, Shimazu, Vandas, Vandas   +26 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Enhanced effective mass in doped SrTiO3 and related perovskites

, 2009
The effective mass is one of the main factors determining the Seebeck coefficient and electronic conductivity. Nb-doping increases the effective mass because of two reasons, lattice constants increase and electronic effects.
Ahrens, Buban, Calvani, Cuong, Fabricius, Frederikse, Hiromichi Ohta, Howard, Imada, Kahn, Kirchheim, Kohiki, Koshibae, Kresse, Kumagai, Kunihito Koumoto, Lee, Lenjer, Luo, Makino, Marques, Metzger, Moos, Morito, Muta, Ohta, Ohta, Ohta, Okuda, Scullin, Shanthi, Suzuki, Tanaka, Turzhevsky, Uchida, Vining, Wang, Wilfried Wunderlich, Wunderlich, Yamamoto, Young, Yu   +41 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source