Results 61 to 70 of about 1,053,987 (302)

Influence of solar forcing, climate variability and modes of low-frequency atmospheric variability on summer floods in Switzerland [PDF]

open access: yesHydrology and Earth System Sciences, 2015
The higher frequency of severe flood events in Switzerland in recent decades has given fresh impetus to the study of flood patterns and their possible forcing mechanisms, particularly in mountain environments.
J. C. Peña   +4 more
doaj   +1 more source

Landslide Susceptibility Mapping in Brazil: A Review

open access: yesGeosciences, 2021
Landslide susceptibility studies are a common type of landslide assessment. Landslides are one of the most frequent hazards in Brazil, resulting in significant economic and social losses (e.g., deaths, injuries, and property destruction).
Helen Cristina Dias   +2 more
doaj   +1 more source

Geological constraints for a conceptual evolutionary model of the slope deformations affecting Mt. Nuovo at Ischia (Italy) [PDF]

open access: yes, 2015
ischia island was the scenario of several Holocene slope in- stability events occurred at different scales, from shallow mass movements, triggered by meteo-climatic forcing, up to massive rock slope failures such as large debris avalanches these last ...
DELLA SETA, Marta   +6 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Determination of Areas Susceptible to Landsliding Using Spatial Patterns of Rainfall from Tropical Rainfall Measuring Mission Data, Rio de Janeiro, Brazil

open access: yesISPRS International Journal of Geo-Information, 2017
Spatial patterns of shallow landslide initiation reflect both spatial patterns of heavy rainfall and areas susceptible to mass movements. We determine the areas most susceptible to shallow landslide occurrence through the calculation of critical soil ...
Renato Fontes Guimarães   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Morphometric and morphostructural analysis as a modeling tool in mass movement scenarios (Bucaramanga, Colombia)

open access: yesGeomatics, Natural Hazards & Risk
The basin is its own environment and sensitive to changes of both natural origin (endogenous and exogenous) and anthropic factors. Due to these changes, especially those of natural origin, basins shape their surfaces by adapting them to these effects ...
Joaquín Andrés Valencia Ortiz   +1 more
doaj   +1 more source

Application of satellite radar interferometry (PSInSAR) in analysis of secondary surface deformations in mining areas. Case studies from Czech Republic and Poland [PDF]

open access: yes, 2018
Secondary deformations are ground movements occurring in areas of ceased underground mining. These are associated with delayed readjustment of rock mass resulting in subsidence, discontinuous deformations (sinks, cracks, etc.) due to destruction of ...
Blachowski, Jan   +4 more
core   +1 more source

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