Results 81 to 90 of about 226,418 (293)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

INHERITANCE OF BASIC QUANTITATIVE TRAITS BY THE HYBRIDS OF GRAIN SORGHUM OF THE FIRST GENERATION

Зерновое хозяйство России, 2018
In the work with all crops including sorghum, it’s necessary to know the character of the inheritance of basic economic traits so that to decrease the time for breeding of new varieties and hybrids.
V. V. Kovtunov
doaj   +2 more sources

Successful long distance road transport of green mussel from Calicut to port Okha. [PDF]

, 1986
The seeds of green mussel were collected from coastal areas at Elathur (north of Calicut) in the morning hours of 26-11-'83, and after cleaning them thoroughly with sea water, without any prior conditioning, were kept in HDPE tanks of about 300-400 litre
Bhaskaran, M M, Khhayya, F D, Trivedi, C R, Wadhw, D J   +3 more
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Physical properties of sesame seeds harvested at different maturation stages and thirds of the plant

Chilean Journal of Agricultural Research, 2018
The quality of sesame (Sesamum indicum L.) seeds is directly influenced by their physical characteristics, which are seldom studied notwithstanding their extreme importance in the entire production chain.
M. E. Araujo, Eloiny Guimarães Barbosa, Felipe A. Gomes, Itamar Rosa Teixeira, C. Lisboa, Rodrigo S. L. Araujo, P. C. Corrêa   +6 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Apollo-Soyuz pamphlet no. 6: Cosmic ray dosage [PDF]

, 1977
The radiation hazard inside spacecraft is discussed with emphasis on its effects on the crew, biological specimens, and spacecraft instruments. The problem of light flash sensations in the eyes of astronauts is addressed and experiment MA-106 is ...
From, T. P., Page, L. W.
core   +1 more source

Percolation of randomly distributed growing clusters: Finite Size Scaling and Critical Exponents

, 2010
We study the percolation properties of the growing clusters model. In this model, a number of seeds placed on random locations on a lattice are allowed to grow with a constant velocity to form clusters.
A. Bunde, D. Stauffer, K. Kosmidis, M. Maragakis, N. Tsakiris, P. Argyrakis   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Condensation of MgS in outflows from carbon stars

, 2008
The basic mechanism responsible for the widespread condensation of MgS in the outflows from carbon rich stars on the tip of the AGB is discussed with the aim of developing a condensation model that can be applied in model calculations of dust formation ...
Allende Prieto, Allende Prieto, Begemann, Bowen, Chaplin, Colangeli, Cox, Daulton, Ferrarotti, Feuchtinger, Fleischer, Fleischer, Forrest, Gail, Gail, Goebel, Grevesse, Grishko, H.-P. Gail, Hashimoto, Henning, Hony, Hony, Hrivnak, Höfner, Höfner, Jeong, Jiang, Kimura, Lagadec, Laor, Lattimer, Nuth, Nuth, Omont, Omont, Papoular, Rouleau, S. Zhukovska, Sloan, Szczerba, van Loon, Vassiliadis, Volk, Winters, Winters, Yamamura, Zijlstra, Zubko   +48 more
core   +1 more source