Results 91 to 100 of about 2,282,439 (313)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Isotope ratio - Mass spectrometry

open access: yes, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article summarizes the configurations involving isotope ratio mass spectrometry (IRMS) technology available at the CCiTUB and the wide range of possible applications. Some examples
Teixidor Casamitjana, Pilar   +2 more
core  

Can gas chromatography combustion isotope ratio mass spectrometry be used to quantify organic compound abundance?

open access: yes, 2011
Quantifying the concentrations of organics such as phospholipid fatty acids (PLFAs) and n-alkanes and measuring their corresponding (13)C/(12)C isotope ratios often involves two separate analyses; (1) quantification by gas chromatography flame ionisation
Sveriges lantbruksuniversitet.   +1 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Analytical estimation of fundamental periods of coupled systems

open access: yesAdvances in Civil and Architectural Engineering
This study provides an in-depth analytical investigation to accurately estimate the seismic responses of coupled systems while considering primary–secondary system interactions (PSSIs).
Omid Fereidooni   +2 more
doaj   +1 more source

Mass-To-Light Ratios of Spiral Galaxies [PDF]

open access: yesSymposium - International Astronomical Union, 1984
Mass-to-light ratios M/LH−0.5 and M/LB are plotted against color B-H−0.5 in Fig. 1 for 82 nearby spirals from the catalog of Aaronson et al. (1982, Ap. J. Suppl. 50, 241), with BT magnitudes from the RC2, |b| > 20°, 45° ≤ i ≤ 80°, and HI mass estimates.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

η → 3 π : Study of the Dalitz Plot and Extraction of the Quark Mass Ratio Q

open access: yes, 2017
The η → 3π amplitude is sensitive to the quark mass difference mu − md and offers a unique way to determine the quark mass ratio Q2 ≡ (m2s − m2ud)/(m2d − m2u) from experiment. We calculate the amplitude dispersively and fit the KLOE Collaboration data on
Passemar, Emilie   +3 more
core   +1 more source

Relativistic dynamics and extreme mass ratio inspirals

open access: yesLiving Reviews in Relativity, 2018
It is now well-established that a dark, compact object, very likely a massive black hole (MBH) of around four million solar masses is lurking at the centre of the Milky Way.
Pau Amaro-Seoane
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy