Results 81 to 90 of about 7,834,536 (290)

Looking through the Mass-to-Charge Ratio: Past, Present and Future Perspectives

open access: yes, 2021
The mass spectrometry (MS) provides the mass-to-charge ratios of atoms, molecules, stable/metastable complexes, and their fragments. I have taken a long journey with MS to address outstanding issues and problems by experiments and theory and gain ...
SHIN, SEUNG KOO
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Mass to Light Ratio and the Initial Mass Function in Galactic Discs [PDF]

open access: yesAstrophysics and Space Science, 2003
A low mass-to-light ratio for the baryonic component of spiral galaxies is advocated by a number of dynamical studies and by cosmological simulations of galaxy formation. We discuss the possibility of obtaining low mass-to-light ratios for the stellar component in discs, by changing the Initial Mass Function and the Star Formation History.
Portinari, L.   +2 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Mass observation / by Mass Observation.

open access: yes, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

Measurement of glutathione synthesis by isotope ratio mass spectrometry in systemic inflammation [PDF]

open access: yes, 2010
During sepsis and critical illness, a systemic inflammatory response can significantly produce reactive oxygen and nitrogen species, which can damage host tissues.
Kimura, Y.
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Mass-To-Light Ratios of Spiral Galaxies [PDF]

open access: yesSymposium - International Astronomical Union, 1984
Mass-to-light ratios M/LH−0.5 and M/LB are plotted against color B-H−0.5 in Fig. 1 for 82 nearby spirals from the catalog of Aaronson et al. (1982, Ap. J. Suppl. 50, 241), with BT magnitudes from the RC2, |b| > 20°, 45° ≤ i ≤ 80°, and HI mass estimates.
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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