Results 121 to 130 of about 907,448 (315)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

The Effectiveness of Population Mass Screening to Oral Cancer: A Simulation Study. [PDF]

Technol Cancer Res Treat, 2022
Su CW, Su WW, Chen SL, Chen TH, Hsu TH, Chen MK, Yen AM.   +6 more
europepmc   +1 more source

Mass Screening of Cardiograms

American Journal of Public Health and the Nations Health, 1962
L D, CADY, M A, WOODBURY, M M, GERTLER, L J, TICK   +3 more
openaire   +3 more sources

Gas chromatographic-mass spectrometric (GC-MS) analysis and virtual screening of ripped fruit of Dialium guineense for potential inhibitors of integrase, cycloxygenase-1, and xanthine oxidase [PDF]

, 2022
Patrick Maduabuchi Aja, Peter Chinedu Agu, Boniface Anthony Ale, J.N. Awoke, Hilary Akobi Ogwoni, Muhammad Akram, E. U. Ekpono, I. O. Igwenyi, Patience N. Ogbu, Okechukwu Paul-Chima Ugwu, Josiah Esoghene Ifie, Sandra Ifie Etumah, Emmanuel Adegboyega Aboyomi, Muhammad Daniyal, Emmanuel Maduabuchi Ezeh, Onyedika Gabriel Ani   +15 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Canine real-time detection of SARS-CoV-2 infections in the context of a mass screening event. [PDF]

BMJ Glob Health, 2022
Ten Hagen NA, Twele F, Meller S, Wijnen L, Schulz C, Schoneberg C, Kreienbrock L, von Köckritz-Blickwede M, Osterhaus A, Boeck AL, Boeck K, Bonda V, Pilchová V, Kaiser FK, Gonzalez Hernandez M, Ebbers H, Hinsenkamp J, Pink I, Drick N, Welte T, Manns MP, Illig T, Puyskens A, Nitsche A, Ernst C, Engels M, Schalke E, Volk HA.   +27 more
europepmc   +1 more source

Multiclass screening in urine by comprehensive two-dimensional liquid chromatography time of flight mass spectrometry for residues of sulphonamides, beta-agonists and steroids

, 2018
Marco Blokland, P.W. Zoontjes, L.A. van Ginkel, Milou G.M. van de Schans, Saskia S. Sterk, Toine F. H. Bovee   +5 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Opinions, practice patterns, and perceived barriers to lung cancer screening among attending and resident primary care physicians

Risk Management and Healthcare Policy, 2018
Louise M Henderson,1 Laura M Jones,1 Mary W Marsh,1 Alison T Brenner,2,3 Adam O Goldstein,4 Thad S Benefield,1 Mikael Anne Greenwood-Hickman,5 Paul L Molina,1 M Patricia Rivera,2 Daniel S Reuland2,3 1Department of Radiology, The University of North ...
Henderson LM, Jones LM, Marsh MW, Brenner AT, Goldstein AO, Benefield TS, Greenwood-Hickman MA, Molina PL, Rivera MP, Reuland DS   +9 more
doaj  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source