Results 121 to 130 of about 6,872,930 (361)

Does Provision of an Evidence-Based Information Change Public Willingness to Accept a Screening Test ? [PDF]

The basic requirement for patient decision making is the provision by the physician of an essential relevant and understandable information (Evidence Based) allowing him to decide whether he wish or not to receive the proposed treatment.
Gianfranco DOMENIGHETTI
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Diagnostic Accuracy of Ascites Fluid Gross Appearance in Detection of Spontaneous Bacterial Peritonitis

Archives of Academic Emergency Medicine, 2014
Introduction: Spontaneous bacterial peritonitis (SBP) as a monomicrobial infection of ascites fluid is one of the most important causes of morbidity and mortality in cirrhotic patients. This study was aimed to determine the diagnostic accuracy of ascites
Hamed Aminiahidashti, Seyed Mohammad Hosseininejad, Hosein Montazer, Farzad Bozorgi, Iraj Goli khatir, Fateme Jahanian, Behnaz Raee   +6 more
doaj   +1 more source

Gastrointestinal cancer screening and surveillance programmes : a worldwide perspective : part 1 [PDF]

, 2012
Part 2 of this article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/13101Cancer is a leading cause of death worldwide and such deaths are projected to continue to rise, creating significant morbidity and ...
Gerada, Jurgen
core  

Taiwan National Newborn Screening Program by Tandem Mass Spectrometry for Mucopolysaccharidoses Types I, II, and VI

Jornal de Pediatria, 2018
Objective To evaluate the initial cutoff values, rates of screen positives, and genotypes for the large‐scale newborn screening program for multiple mucopolysaccharidoses (MPS) in Taiwan.
Min-Ju Chan, Hsuan-Chieh Liao, M. Gelb, C. Chuang, Mei‐Ying Liu, Hsiao-Jan Chen, S. Kao, Hsiang-Yu Lin, You-Hsin Huang, A. Kumar, N. Chennamaneni, Nagendar Pendem, Shuan-Pei Lin, C. Chiang   +13 more
semanticscholar   +1 more source

Mass screening in modified gravity

Classical and Quantum Gravity, 2008
Models of modified gravity introduce extra degrees of freedom, which for consistency with the data, should be suppressed at observable scales. In the models that share properties of massive gravity such a suppression is due to nonlinear interactions: An isolated massive astrophysical object creates a halo of a nonzero curvature around it, shielding its
Gabadadze, Gregory, Iglesias, Alberto
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Prevalence and under-detection of gambiense human African trypanosomiasis during mass screening sessions in Uganda and Sudan [PDF]

, 2012
BACKGROUND: Active case detection through mass community screening is a major control strategy against human African trypanosomiasis (HAT, sleeping sickness) caused by T. brucei gambiense.
Haydon Daniel T, Chappuis, F., Cox, A.P., Cox Andrew P, Checchi Francesco, Haydon, D.T., Priotto Gerardo, Priotto, Gerardo, Checchi, Francesco, Chandramohan, Daniel, Priotto, G., Haydon, Daniel T, Cox, Andrew P, Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +17 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Patients' & Healthcare Professionals' Values Regarding True- & False-Positive Diagnosis when Colorectal Cancer Screening by CT Colonography: Discrete Choice Experiment. [PDF]

, 2013
To establish the relative weighting given by patients and healthcare professionals to gains in diagnostic sensitivity versus loss of specificity when using CT colonography (CTC) for colorectal cancer ...
von Wagner, Christian, Bell, N., Douglas G Altman, Boone, D., Yao, G. L., Boone, Darren, Halligan, S, Ghanouni, A., Darren Boone, Taylor, Stuart A, Altman, Douglas G, von Wagner, C, Lilford, R, Yao, G.L., Halligan, S., Bell, N, Boone, D, Taylor, S.A., Nichola Bell, Taylor, S. A., Altman, DG, Guiqing Lily Yao, Altman, Douglas G., Ghanouni, Alex, Mallett, S, Bell, Nichola, Mallett, S., Richard Lilford, Zhu, S, Mallett, Susan, Susan Mallett, Boone, David L., Taylor, SA, Alex Ghanouni, Yao, Guiqing Lily, Yao, GL, Lilford, Richard, Stuart A Taylor, Shihua Zhu, Christian von Wagner, Halligan, Steve, Altman, D.G., Zhu, Shihua, Ghanouni, A, Lilford, R., Zhu, S., von Wagner, C., Steve Halligan   +47 more
core   +1 more source