Results 211 to 220 of about 1,771,429 (303)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A Novel Point-of-Care Prediction Model for Steatotic Liver Disease: Expected Role of Mass Screening in the Global Obesity Crisis. [PDF]

Gut Liver
Park J, Chung GE, Chang Y, Kim SE, Sohn W, Ryu S, Ko Y, Park Y, Hur MH, Lee YB, Cho EJ, Lee JH, Yu SJ, Yoon JH, Kim YJ.   +14 more
europepmc   +1 more source

Erratum in: Real-Time Risk Score for Glaucoma Mass Screening by Spectral Domain Optical Coherence Tomography: Development and Validation. [PDF]

Transl Vis Sci Technol, 2023
europepmc   +1 more source

Mass Screening of SARS-CoV-2 Variants using Sanger Sequencing Strategy in Hiroshima, Japan. [PDF]

Sci Rep, 2022
Ko K, Takahashi K, Nagashima S, E B, Ouoba S, Hussain MRA, Akita T, Sugiyama A, Sakaguchi T, Tahara H, Ohge H, Ohdan H, Kubo T, Ishikawa N, Takafuta T, Fujii Y, Mimori M, Okada F, Kishita E, Ariyoshi K, Kuwabara M, Tanaka J.   +21 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Impact of Mass Screening Using Chest X-Ray on Mortality Reduction and Treatment Adherence Among Pulmonary Tuberculosis Patients. [PDF]

J Korean Med Sci
Baek JY, Kazmi SZ, Lee H, Hwang Y, Park SJ, Shin MH, Lee J, Choi H, Shin A.   +8 more
europepmc   +1 more source

Rapid antigen detection alone may not be sufficient for early diagnosis and/or mass screening of COVID-19. [PDF]

J Med Virol, 2021
Wan Z, Zhao Y, Lu R, Dong Y, Zhang C.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

New cheaper human papilloma virus mass screening strategy reduces cervical cancer incidence in Changsha city: A clinical trial. [PDF]

World J Clin Oncol
Zu YE, Wang SF, Peng XX, Wen YC, Shen XX, Wang XL, Liao WB, Jia D, Liu JY, Peng XW.   +9 more
europepmc   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source